Reaction profile

The FDA adverse-event record for neurological disorder nos

553 FDA adverse-event reports reference neurological disorder nos (VeDDRA 2728). See the species, breeds, and drugs most associated with it below.

553
reports citing this reaction
27.7%
death-coded share
Dog
most-affected species
Bedinvetmab
most-associated drug
Verify with FDA CVM →
553
Total Reports
153
Deaths
27.7%
Death Rate

Species Most Affected

Dog 423
Cat 122
Horse 5
Sheep 1
Human 1
Cattle 1

Breeds Most Affected

Domestic Shorthair 66
Retriever - Labrador 47
Dog (unknown) 37
Crossbred Canine/dog 24
Retriever - Golden 23
Chihuahua 22
Shepherd Dog - German 16
Terrier - Yorkshire 14
Boxer (German Boxer) 13
Shepherd Dog - Australian 12

Associated Drugs

Bedinvetmab 163
Pyrantel Pamoate;Sarolaner 51
Gabapentin 43
Maropitant Citrate 38
Carprofen 34
Buprenorphine 27
Fluralaner 13.64% 12-Week Chew 25
Sarolaner 24
Milbemycin Oxime + Praziquantel 21
Lotilaner 20
Selamectin 18
Oclacitinib Maleate 17
Frunevetmab 17
Milbemycin Oxime + Spinosad 15
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 14
Grapiprant 13
Trilostane 12
Imidacloprid + Moxidectin 11
Enrofloxacin 11
Fluralaner Spot-On Solution 11

Neurological disorder NOS Reaction Insights

553 reports name Neurological disorder NOS; 153 recorded a death outcome (27.7% of reported events, not a population-level mortality rate). VeDDRA code: 2728.

By species: Dog (423 reports), Cat (122 reports), Horse (5 reports). By breed: Domestic Shorthair (66), Retriever - Labrador (47), Dog (unknown) (37).

Most co-reported drugs: Bedinvetmab (163 reports), Pyrantel Pamoate;Sarolaner (51 reports), Gabapentin (43 reports), Maropitant Citrate (38 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.