Reaction profile

The FDA adverse-event record for pr-muscle(s), lesion(s)

42 FDA reports name pr-muscle(s), lesion(s), a lower-volume reaction in the CVM extract (VeDDRA 99654). Plate stamps and neighbourhood peers follow.

#1835 of 2,481
by report volume (all reactions)
42
reports citing this reaction
90.5%
death-coded share
Dog
most-affected species
Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. PR-MUSCLE(S), LESION(S) has 42 reports now versus 42 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to PR-MUSCLE(S), LESION(S) changes

FDA AER · VeDDRA plate

Code 99654 VOL-TRACE

VOL-TRACE · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 42 reports
  • DEATH-HOT 90.5%
  • MID-PACK #1835/2481
  • PHOTO-FINISH Allergy to food
  • SPECIES-DOG Dog · 18
  • DRUG-LEAD Carprofen · 7
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Allergy to food (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around PR-MUSCLE, LESION

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Allergy to food · near42Asystole · near42Cholecystitis · near42Cutaneous emphysema · near42PR-MUSCLE(S), LESION(… · thi…42Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around PR-MUSCLE(S), LESION(S)

PR-MUSCLE(S), LESION(S): high death-coded share in the FDA AER plate

Signature read: PR-MUSCLE(S), LESION(S)'s 90.5% death-coded share is among the highest in the openFDA reaction corpus. Report volume is lower-third scale: 42 named reports in the openFDA extract. Death-coded share is upper-third: 38 of 42 reports (90.5% of named reports). Nearest volume peer: Allergy to food (±0 reports). Lead species Dog (18). Lead co-reported drug Carprofen (7).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 18
Cattle 10
Horse 6
Cat 5
Pig 2
Quail 1

Breeds Most Affected

Holstein-Friesian also known as Holstein 6
Retriever - Labrador 5
Collie - Border 4
Domestic Shorthair 3
Crossbred Bovine/Cattle 2
Thoroughbred 2
Mastiff 2
Pig (unknown) 2
Quarter Horse 2
Domestic (unspecified) 1

Associated Drugs

Carprofen 7
Dinoprost Tromethamine 6
Cefovecin 4
Buprenorphine 3
Clostridium Chauvoei, Strain F, Lot No. 2-84; Clostridium Novyi, 8296, Kb; Clost 3
Oclacitinib Maleate 3
Dexmedetomidine Hydrochloride 2
Anesthetic 2
Dexamethasone 2
Ceftiofur Crystalline Free Acid 2
Tramadol 2
Doxycycline 2
Prednisone 2
Fluralaner Chew Tablets 2
Cefovecin Sodium 1
Ivermectin 1
Selamectin 1
Prednisolone Sodium Succinate 1
Ceftiofur 1
Monensin 1

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for PR-MUSCLE(S), LESION(S) (#1835 of 2,481 by report volume); death-coded 90.5%. PlainBreed reaction plate · death-coded share stamp 90.5% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →