Reaction profile

The FDA adverse-event record for self trauma

1,400 FDA reports name self trauma, a high-volume reaction in the CVM extract (VeDDRA 125). Plate stamps and neighbourhood peers follow.

#301 of 2,481
by report volume (all reactions)
1,400
reports citing this reaction
2.0%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Self trauma has 1,400 reports now versus 1,391 in that prior snapshot: 9 more (0.6%).

Report change
+9
Death-coded reports
+1
Death-coded share
+0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Self trauma changes

FDA AER · VeDDRA plate

Code 125 VOL-MID

VOL-MID · DEATH-LOW · UPPER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 1,400 reports
  • DEATH-LOW 2.0%
  • UPPER-Q #301/2481
  • PHOTO-FINISH Tarry or black stool…
  • SPECIES-DOG Dog · 1,127
  • DRUG-LEAD Milbemycin Oxime… · 281
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Tarry or black stool (see also haemorrhagic diarrhoea) (±4 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Self trauma

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Self trauma · this reaction1400Tarry or black stool… · near1396Wobbliness · near1396Decreased red blood c… · near1394Glucosuria · near1391Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Self trauma

Self trauma: low death-coded share in the FDA AER plate

Signature read: 1,400 reports place Self trauma in the upper third of FDA AER volume (#301 of 2,481). Report volume is upper-third scale: 1,400 named reports in the openFDA extract. Death-coded share is lower-third: 28 of 1,400 reports (2.0% of named reports). Nearest volume peer: Tarry or black stool (see also haemorrhagic diarrhoea) (±4 reports). Lead species Dog (1,127). Lead co-reported drug Milbemycin Oxime + Spinosad (281).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Milbemycin Oxime + Spinosad appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 1,127
Cat 259
Horse 9
Unknown 2
Human 2
Cattle 1

Breeds Most Affected

Domestic Shorthair 168
Retriever - Labrador 113
Shih Tzu 65
Shepherd Dog - German 63
Crossbred Canine/dog 61
Chihuahua 59
Maltese 43
Retriever - Golden 42
Dog (unknown) 41
Terrier - Yorkshire 38

Associated Drugs

Milbemycin Oxime + Spinosad 281
Afoxolaner 236
Spinosad 155
Ivermectin + Pyrantel As Pamoate Salt 90
Nitenpyram 86
Selamectin 66
Imidacloprid + Moxidectin 60
Fluralaner Chew Tablets 51
Fluralaner Spot-On Solution 37
Carprofen 25
Afoxolaner 28.3 Mg Chewable Tablets 25
Cyclosporine 23
Frunevetmab 21
Oclacitinib Maleate 20
Milbemycin Oxime + Praziquantel 20
Fluralaner 13.64% 12-Week Chew 19
Ivermectin 18
Lotilaner 17
Cefovecin 16
Fluralaner/Moxidectin Spot-On 14

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Self trauma, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (2.0% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Self trauma (#301 of 2,481 by report volume); death-coded 2.0%. PlainBreed reaction plate · report volume stamp 1,400 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →