Increased lung sounds

Verify with FDA CVM →

VeDDRA Code: 2488

147 adverse event reports referencing this reaction

147
Total Reports
57
Deaths
3880.0%
Death Rate

Species Most Affected

Dog 112
Cat 30
Horse 4
Cattle 1

Breeds Most Affected

Domestic Shorthair 21
Retriever - Labrador 17
Crossbred Canine/dog 8
Boxer (German Boxer) 6
Terrier - Yorkshire 5
Shepherd Dog - German 4
Terrier (unspecified) 4
Shih Tzu 4
Pug 4
Beagle 4

Associated Drugs

Maropitant Citrate 25
Furosemide 12
Buprenorphine 12
Butorphanol 12
Carprofen 11
Moxidectin 10
Gabapentin 10
Prednisone 9
Dexamethasone 8
Afoxolaner 8
Oclacitinib Maleate 8
Enrofloxacin 8
Ivermectin + Pyrantel As Pamoate Salt 8
Melarsomine Dihydrochloride 8
Fluralaner Chew Tablets 7
Cefovecin 7
Oxygen 7
Propofol 7
Famotidine 6
Amoxicillin 6

Data Summary

Metric Value
Total reports referencing reaction 147
Reports with fatal outcome 57
Case-fatality rate (reported events) 3880.0%
Species observed 4
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 2488.

Increased lung sounds Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 147 adverse event reports that reference Increased lung sounds as a reaction term, including 57 reports with a death outcome — a 3880.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 2488, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Increased lung sounds appears most frequently in reports for Dog (112 reports), Cat (30 reports), Horse (4 reports) — with Dog dominating at 112 entries. Within those species, the breeds most often named alongside this reaction are Domestic Shorthair (21), Retriever - Labrador (17), Crossbred Canine/dog (8). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Increased lung sounds are Maropitant Citrate (25 reports), Furosemide (12 reports), Buprenorphine (12 reports), Butorphanol (12 reports), with Maropitant Citrate appearing alongside this reaction in 25 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial