Reaction profile

The FDA adverse-event record for elevated serum amyloid a (saa)

Name: Elevated serum amyloid A (SAA) - FDA Animal Adverse Reaction
Creator: PlainBreed
License: https://open.fda.gov/license/

13 FDA reports name elevated serum amyloid a (saa), a lower-volume reaction in the CVM extract (VeDDRA 3179). Plate stamps and neighbourhood peers follow.

#2352 of 2,481
by report volume (all reactions): 13
reports citing this reaction: 30.8%
death-coded share: Horse
most-affected species

Compiled by PlainBreed

Verify with FDA CVM →

FDA AER · VeDDRA plate

Code 3179 VOL-TRACE

VOL-TRACE · DEATH-HOT · BOTTOM-DECILE · PHOTO-FINISH · SPECIES-HORSE · DRUG-LEAD · DESK-WIDE · BOOK-FULL

VOL-TRACE 13 reports
DEATH-HOT 30.8%
BOTTOM-DECILE #2352/2481
PHOTO-FINISH Abnormal digital pulse
SPECIES-HORSE Horse · 13
DRUG-LEAD Flunixin Meglumin… · 3
DESK-WIDE 9 breeds
BOOK-FULL 8/8 fields

Nearest volume peer: Abnormal digital pulse (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around Elevated serum amyloid A

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

FDA AER report volume · neighbourhood around Elevated serum amyloid A (SAA)

Elevated serum amyloid A (SAA): high death-coded share in the FDA AER plate

Signature read: 13 reports place Elevated serum amyloid A (SAA) in the lower third of FDA AER volume (#2352 of 2,481). Report volume is lower-third scale: 13 named reports in the openFDA extract. Death-coded share is upper-third: 4 of 13 reports (30.8% of named reports). Nearest volume peer: Abnormal digital pulse (±0 reports). Lead species Horse (13). Lead co-reported drug Flunixin Meglumine Injectable (3).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Horse 13

Breeds Most Affected

Quarter Horse 4

Miniature 2

Paint 1

Thoroughbred 1

Horse (other) 1

Warmblood - Dutch 1

Warmblood (unspecified) 1

Crossbred Equine/horse 1

Standardbred - American 1

Associated Drugs

Flunixin Meglumine Injectable 3

Hyaluronate Sodium 3

Clodronate Disodium 3

Acetaminophen 3

Firocoxib 2

Ceftiofur Crystalline Free Acid 2

Betavet 2

Water, Sodium Chloride, Sodium Gluconate, Sodium Acetate Trihydrate, Potassium Chloride, Magnesium Chloride 2

Water, Sodium Chloride 2

Furosemide 2

Polysulfated Glycosaminoglycan 1

Oxytetracycline Dihydrate (Oxytetracycline Amphoteric) 1

Sulfadiazine And Trimethoprim 1

Saline 1

Amikacin 1

Betamethasone 1

Gentamicin 1

Phenylbutazone 1

Detomidine 1

Butorphanol 1

What to do with this reaction

Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
Browse the full reaction directory to compare report counts across reaction types. All reactions

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Elevated serum amyloid A (SAA) (#2352 of 2,481 by report volume); death-coded 30.8%. PlainBreed reaction plate · report volume stamp 13 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →