Reaction profile

The FDA adverse-event record for arthropathy nos

44 FDA adverse-event reports reference arthropathy nos (VeDDRA 1335). See the species, breeds, and drugs most associated with it below.

44
reports citing this reaction
31.8%
death-coded share
Dog
most-affected species
Bedinvetmab
most-associated drug
Verify with FDA CVM →
44
Total Reports
14
Deaths
31.8%
Death Rate

Species Most Affected

Dog 37
Cat 5
Sheep 1
Cattle 1

Breeds Most Affected

Retriever - Labrador 8
Crossbred Canine/dog 4
Siberian Husky 3
Shih Tzu 2
Retriever - Golden 2
Shepherd Dog - German 2
Dog (unknown) 2
Domestic Mediumhair 2
Spaniel - King Charles Cavalier 2
Dachshund (unspecified) 1

Associated Drugs

Bedinvetmab 13
Carprofen 9
Gabapentin 8
Trilostane 7
Milbemycin Oxime + Spinosad 4
Grapiprant 4
Frunevetmab 4
Meloxicam 3
Buprenorphine 3
Polysulfated Glycosaminoglycan 3
Amantadine 3
Oclacitinib Maleate 2
Cefpodoxime 2
Tramadol 2
Fluralaner 13.64% 12-Week Chew 2
Lotilaner 2
Maropitant Citrate 2
Prednisone 2
Trazodone 2
Doxycycline 2

Arthropathy NOS Reaction Insights

44 reports name Arthropathy NOS; 14 recorded a death outcome (31.8% of reported events, not a population-level mortality rate). VeDDRA code: 1335.

By species: Dog (37 reports), Cat (5 reports), Sheep (1 reports). By breed: Retriever - Labrador (8), Crossbred Canine/dog (4), Siberian Husky (3).

Most co-reported drugs: Bedinvetmab (13 reports), Carprofen (9 reports), Gabapentin (8 reports), Trilostane (7 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.