Reaction profile

The FDA adverse-event record for increased intra-ocular pressure

95 FDA adverse-event reports reference increased intra-ocular pressure (VeDDRA 2234). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1421 of 2,481
by report volume (all reactions)
95
reports citing this reaction
18.9%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Increased intra-ocular pressure has 95 reports now versus 90 in that prior snapshot: 5 more (5.6%).

Report change
+5
Death-coded reports
+1
Death-coded share
+0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Increased intra-ocular pressure changes

FDA AER · VeDDRA plate

Code 2234 VOL-LOW

VOL-LOW · DEATH-ELEV · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 95 reports
  • DEATH-ELEV 18.9%
  • MID-PACK #1421/2481
  • PHOTO-FINISH Chemical burn
  • SPECIES-DOG Dog · 78
  • DRUG-LEAD Florfenicol + Mom… · 10
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Chemical burn (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Increased intra-ocular pressure

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Chemical burn · near95Head twitching · near95Increased intra-ocula… · thi…95Respiratory depression · near95Vision blurred · near95Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Increased intra-ocular pressure

What the FDA AER plate says about Increased intra-ocular pressure

Signature read: death-coded share at 18.9% is the most distinctive outcome stamp on Increased intra-ocular pressure. Report volume sits in the middle third of the reaction corpus. 18 of 95 reports were death-coded (18.9% of named reports, not a population mortality rate). Nearest volume peer: Chemical burn (±0 reports). Lead species Dog (78). Lead co-reported drug Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride (10).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 78
Cat 16
Rabbit 1

Breeds Most Affected

Domestic Shorthair 14
Shih Tzu 9
Retriever - Labrador 7
Spaniel - Cocker American 4
Siberian Husky 4
Bulldog - French 4
Collie - Border 3
Lhasa Apso 2
Pug 2
Terrier (unspecified) 2

Associated Drugs

Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 10
Carprofen 9
Prednisone 8
Maropitant Citrate 7
Pyrantel Pamoate;Sarolaner 7
Bedinvetmab 7
Moxidectin 6
Cefovecin Sodium 6
Diphenhydramine 5
Fluralaner Chew Tablets 5
Trilostane 5
Doxycycline 5
Metronidazole 4
Meloxicam 4
Grapiprant 4
Isoflurane 4
Leptospirosis Vaccine 4
Milbemycin Oxime + Spinosad 3
Oclacitinib Maleate 3
Atipamezole Hydrochloride 3

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Increased intra-ocular pressure, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (95 here).

Similar death-coded share

Nearest other reactions by death-coded share (18.9% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Increased intra-ocular pressure (#1421 of 2,481 by report volume); death-coded 18.9%. PlainBreed reaction plate · death-coded share stamp 18.9% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →