Reaction profile

The FDA adverse-event record for copper deficiency signs

16 FDA reports name copper deficiency signs, a lower-volume reaction in the CVM extract (VeDDRA 561). Plate stamps and neighbourhood peers follow.

#2264 of 2,481
by report volume (all reactions)
16
reports citing this reaction
87.5%
death-coded share
Cattle
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Copper deficiency signs has 16 reports now versus 16 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Copper deficiency signs changes

FDA AER · VeDDRA plate

Code 561 VOL-TRACE

VOL-TRACE · DEATH-HOT · BOTTOM-DECILE · PHOTO-FINISH · SPECIES-CATTLE · DRUG-LEAD · DESK-MID · BOOK-FULL

  • VOL-TRACE 16 reports
  • DEATH-HOT 87.5%
  • BOTTOM-DECILE #2264/2481
  • PHOTO-FINISH Abdominal transudate
  • SPECIES-CATTLE Cattle · 14
  • DRUG-LEAD Tulathromycin · 5
  • DESK-MID 6 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Abdominal transudate (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around Copper deficiency signs

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Abdominal transudate · near16Abnormal rectal palpa… · near16AMMONIA INCREASED, BL… · near16Application site gran… · near16Copper deficiency sig… · thi…16Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Copper deficiency signs

Copper deficiency signs: high death-coded share in the FDA AER plate

Signature read: Copper deficiency signs's 87.5% death-coded share is among the highest in the openFDA reaction corpus. Report volume is lower-third scale: 16 named reports in the openFDA extract. Death-coded share is upper-third: 14 of 16 reports (87.5% of named reports). Nearest volume peer: Abdominal transudate (±0 reports). Lead species Cattle (14). Lead co-reported drug Tulathromycin (5).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Cattle 14
Horse 1
Sheep 1

Breeds Most Affected

Cattle (other) 9
Mixed (Cattle) 3
Cattle (unknown) 1
Quarter Horse 1
Aberdeen Angus 1
Lincoln 1

Associated Drugs

Tulathromycin 5
Ceftiofur Crystalline Free Acid 4
Bovine Parainfluenza Virus 3 (Ts), Rlb103 (Nl-Bk-6), Mlv; Bovine Respiratory Syn 3
Doramectin 3
Oxytetracycline 2
Moxidectin 2
Albendazole 2
Bovine Parainfluenza 3, Pi3 Ebk-1/Ebht-1 Strain Al-Im;Bovine Respiratory Syncyti 2
Bovine Parainfluenzavirus 3,Reisinger(Nl-Bk-6), Mlv; Bovine Viral Diarrhea Virus 1
Clostridium Chauvoei, F, Kb; Clostridium Novyi, 8296, Kb; Clostridium Perfringen 1
Chlortetracycline + Roxarsone + Salinomycin 1
Gamithromycin 15% 1
Bovine Respiratory Syncytial Virus, Brsv375, Mlv; Bovine Viral Diarrhea Virus, 5 1
Bovine Parainfluenza Virus 3, Reisinger(Nl-Bk-6), Mlv; Bovine Respiratory Syncyt 1
Clostridium Chauvoei, F, Kb; Clostridium Haemolyticum, Irp-135, Kb; Clostridium 1
Bovine Viral Diarrhea Virus, 53637, Bvd2Mlv-D; Bovine Viral Diarrhea Virus, Nadl 1
Xylazine 1
Penicillin G Procaine 1
Bovine Respiratory Syncytial Virus, 597-10 10Th Psg Strain 375; Bovine Viral Dia 1
Multi-Vitamin 1

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Copper deficiency signs (#2264 of 2,481 by report volume); death-coded 87.5%. PlainBreed reaction plate · death-coded share stamp 87.5% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →