Copper deficiency signs

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VeDDRA Code: 561

15 adverse event reports referencing this reaction

15
Total Reports
13
Deaths
8670.0%
Death Rate

Species Most Affected

Cattle 13
Horse 1
Sheep 1

Breeds Most Affected

Cattle (other) 9
Mixed (Cattle) 2
Cattle (unknown) 1
Quarter Horse 1
Aberdeen Angus 1
Lincoln 1

Associated Drugs

Tulathromycin 5
Bovine Parainfluenza Virus 3 (Ts), Rlb103 (Nl-Bk-6), Mlv; Bovine Respiratory Syn 3
Ceftiofur Crystalline Free Acid 3
Doramectin 2
Oxytetracycline 2
Moxidectin 2
Albendazole 2
Bovine Parainfluenzavirus 3,Reisinger(Nl-Bk-6), Mlv; Bovine Viral Diarrhea Virus 1
Clostridium Chauvoei, F, Kb; Clostridium Novyi, 8296, Kb; Clostridium Perfringen 1
Chlortetracycline + Roxarsone + Salinomycin 1
Gamithromycin 15% 1
Bovine Parainfluenza Virus 3, Reisinger(Nl-Bk-6), Mlv; Bovine Respiratory Syncyt 1
Clostridium Chauvoei, F, Kb; Clostridium Haemolyticum, Irp-135, Kb; Clostridium 1
Bovine Respiratory Syncytial Virus, Brsv375, Mlv; Bovine Viral Diarrhea Virus, 5 1
Bovine Viral Diarrhea Virus, 53637, Bvd2Mlv-D; Bovine Viral Diarrhea Virus, Nadl 1
Xylazine 1
Penicillin G Procaine 1
Bovine Respiratory Syncytial Virus, 597-10 10Th Psg Strain 375; Bovine Viral Dia 1
Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza3-Respiratory Syncytial Virus Vaccine, Modified Live Virus, Mannheimia Haemolytica Toxoid 1
Multi-Vitamin 1

Data Summary

Metric Value
Total reports referencing reaction 15
Reports with fatal outcome 13
Case-fatality rate (reported events) 8670.0%
Species observed 3
Breeds observed 6
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 561.

Copper deficiency signs Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 15 adverse event reports that reference Copper deficiency signs as a reaction term, including 13 reports with a death outcome — a 8670.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 561, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Copper deficiency signs appears most frequently in reports for Cattle (13 reports), Horse (1 reports), Sheep (1 reports) — with Cattle dominating at 13 entries. Within those species, the breeds most often named alongside this reaction are Cattle (other) (9), Mixed (Cattle) (2), Cattle (unknown) (1). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Copper deficiency signs are Tulathromycin (5 reports), Bovine Parainfluenza Virus 3 (Ts), Rlb103 (Nl-Bk-6), Mlv; Bovine Respiratory Syn (3 reports), Ceftiofur Crystalline Free Acid (3 reports), Doramectin (2 reports), with Tulathromycin appearing alongside this reaction in 5 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial