Reaction profile

The FDA adverse-event record for alkalosis

86 FDA adverse-event reports reference alkalosis (VeDDRA 2075). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1466 of 2,481
by report volume (all reactions)
86
reports citing this reaction
25.6%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Alkalosis has 86 reports now versus 83 in that prior snapshot: 3 more (3.6%).

Report change
+3
Death-coded reports
+1
Death-coded share
+0.3 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Alkalosis changes

FDA AER · VeDDRA plate

Code 2075 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 86 reports
  • DEATH-HOT 25.6%
  • MID-PACK #1466/2481
  • PHOTO-FINISH Application site pust…
  • SPECIES-DOG Dog · 56
  • DRUG-LEAD Gabapentin · 14
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Application site pustule (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Report-volume neighbourhood around Alkalosis

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Alkalosis · this reaction86Application site pust… · near86Conjunctival oedema · near86Eyelid inflammation · near86Hypercortisolaemia · near86Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Alkalosis

Alkalosis: high death-coded share in the FDA AER plate

Signature read: Alkalosis's 25.6% death-coded share is among the highest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is upper-third: 22 of 86 reports (25.6% of named reports). Nearest volume peer: Application site pustule (±0 reports). Lead species Dog (56). Lead co-reported drug Gabapentin (14).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 56
Cat 23
Horse 5
Donkey 1
Goat 1

Breeds Most Affected

Domestic Shorthair 12
Retriever - Labrador 9
Domestic Longhair 4
Quarter Horse 3
Bulldog - French 3
Retriever - Golden 3
Crossbred Canine/dog 3
Schnauzer - Miniature 2
Shepherd Dog - German 2
Shepherd Dog - Australian 2

Associated Drugs

Gabapentin 14
Maropitant Citrate 12
Carprofen 10
Buprenorphine 9
Milbemycin Oxime + Spinosad 8
Enrofloxacin 8
Bexagliflozin 8
Afoxolaner 6
Oxygen 6
Fluid Therapy 6
Ampicillin Sodium/Sulbactam Sodium 5
Oclacitinib Maleate 4
Ivermectin + Pyrantel As Pamoate Salt 4
Propofol 4
Isoflurane 4
Pantoprazole 4
Trilostane 4
Lotilaner 4
Rabies Vaccine 4
Maropitant 4

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Alkalosis, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (86 here).

Similar death-coded share

Nearest other reactions by death-coded share (25.6% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Alkalosis (#1466 of 2,481 by report volume); death-coded 25.6%. PlainBreed reaction plate · death-coded share stamp 25.6% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →