Distress

VeDDRA Code: 114

751 adverse event reports referencing this reaction

751

Total Reports

134

Deaths

1780.0%

Death Rate

Species Most Affected

Dog 431

Cat 255

Horse 30

Pig 17

Cattle 13

Sheep 2

Chicken 1

Rabbit 1

Turkey 1

Breeds Most Affected

Domestic Shorthair 143

Crossbred Canine/dog 37

Retriever - Labrador 35

Cat (unknown) 32

Domestic Longhair 29

Chihuahua 21

Retriever - Golden 18

Dog (unknown) 17

Shih Tzu 16

Shepherd Dog - German 13

Associated Drugs

Milbemycin Oxime + Spinosad 64

Buprenorphine 48

Maropitant Citrate 42

Nitenpyram 35

Gabapentin 32

Bexagliflozin 31

Afoxolaner 26

Carprofen 25

Bedinvetmab 25

Trilostane 24

Fluralaner Spot-On Solution 23

Spinosad 22

Polysulfated Glycosaminoglycan 22

Robenacoxib 20

Selamectin 19

Ivermectin + Pyrantel As Pamoate Salt 19

Prednisone 18

Lotilaner 18

Ractopamine Hydrochloride 17

Meloxicam 17

Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.