Reaction profile

The FDA adverse-event record for haemolysis nos

162 FDA adverse-event reports reference haemolysis nos (VeDDRA 2156). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1145 of 2,481
by report volume (all reactions)
162
reports citing this reaction
16.7%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Haemolysis NOS has 162 reports now versus 153 in that prior snapshot: 9 more (5.9%).

Report change
+9
Death-coded reports
+1
Death-coded share
−0.3 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Haemolysis NOS changes

FDA AER · VeDDRA plate

Code 2156 VOL-LOW

VOL-LOW · DEATH-ELEV · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 162 reports
  • DEATH-ELEV 16.7%
  • MID-PACK #1145/2481
  • PHOTO-FINISH Dazed
  • SPECIES-DOG Dog · 137
  • DRUG-LEAD Trilostane · 126
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Dazed (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Haemolysis NOS

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Bronchopneumonia · near163Dazed · near162Haemolysis NOS · this reacti…162Meningitis · near162Pancytopenia · near162Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Haemolysis NOS

What the FDA AER plate says about Haemolysis NOS

Signature read: 27 death-coded reports is the most distinctive absolute-outcome stamp on Haemolysis NOS. Report volume sits in the middle third of the reaction corpus. 27 of 162 reports were death-coded (16.7% of named reports, not a population mortality rate). Nearest volume peer: Dazed (±0 reports). Lead species Dog (137). Lead co-reported drug Trilostane (126).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Trilostane appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 137
Cat 22
Horse 2
Cattle 1

Breeds Most Affected

Domestic Shorthair 14
Chihuahua 13
Retriever - Labrador 11
Maltese 8
Crossbred Canine/dog 8
Terrier - Yorkshire 7
Terrier (unspecified) 6
Shepherd Dog - German 6
Pinscher - Miniature 4
Terrier - Boston 4

Associated Drugs

Trilostane 126
Bexagliflozin 15
Desoxycortone Pivalate 14
Gabapentin 14
Prednisone 13
Carprofen 12
Grapiprant 8
Metronidazole 7
Maropitant Citrate 7
Benazepril 6
Pimobendan 6
Fluoxetine 5
Fluralaner 13.64% 12-Week Chew 5
Oclacitinib Maleate 5
Ursodiol 5
Water, Sodium Chloride, Sodium Lactate, Potassium Chloride, Calcium Chloride 5
Doxycycline 5
Leptospirosis Vaccine 5
Ivermectin/Pyrantel 4
Afoxolaner 4

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Haemolysis NOS, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (162 here).

Similar death-coded share

Nearest other reactions by death-coded share (16.7% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Haemolysis NOS (#1145 of 2,481 by report volume); death-coded 16.7%. PlainBreed reaction plate · death-coded report count stamp 27 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →