Reaction profile

The FDA adverse-event record for milk production increase

Name: Milk production increase - FDA Animal Adverse Reaction
Creator: PlainBreed
License: https://open.fda.gov/license/

15 FDA reports name milk production increase, a lower-volume reaction in the CVM extract (VeDDRA 536). Plate stamps and neighbourhood peers follow.

#2308 of 2,481
by report volume (all reactions): 15
reports citing this reaction: 13.3%
death-coded share: Cattle
most-affected species

Compiled by PlainBreed

Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Milk production increase has 15 reports now versus 15 in that prior snapshot: 0 the same number of (0.0%).

Report change: +0
Death-coded reports: +0
Death-coded share: +0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Milk production increase changes

FDA AER · VeDDRA plate

Code 536 VOL-TRACE

VOL-TRACE · DEATH-ELEV · BOTTOM-DECILE · PHOTO-FINISH · SPECIES-CATTLE · DRUG-LEAD · DESK-MID · BOOK-FULL

VOL-TRACE 15 reports
DEATH-ELEV 13.3%
BOTTOM-DECILE #2308/2481
PHOTO-FINISH Abomasal ulcer
SPECIES-CATTLE Cattle · 10
DRUG-LEAD Monensin Sodium · 6
DESK-MID 7 breeds
BOOK-FULL 8/8 fields

Nearest volume peer: Abomasal ulcer (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Milk production increase

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

FDA AER report volume · neighbourhood around Milk production increase

What the FDA AER plate says about Milk production increase

Signature read: 15 reports place Milk production increase in the lower third of FDA AER volume (#2308 of 2,481). Report volume is lower-third scale: 15 named reports in the openFDA extract. 2 of 15 reports were death-coded (13.3% of named reports, not a population mortality rate). Nearest volume peer: Abomasal ulcer (±0 reports). Lead species Cattle (10). Lead co-reported drug Monensin Sodium (6).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Monensin Sodium appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Cattle 10

Dog 4

Horse 1

Breeds Most Affected

Holstein-Friesian also known as Holstein 9

Chihuahua 1

Poodle (unspecified) 1

Catahoula Leopard Dog 1

Quarter Horse 1

Hereford cattle 1

Pit Bull 1

Associated Drugs

Monensin Sodium 6

Sometribove Zinc Suspension 4

Sometribove 3

Milbemycin Oxime + Spinosad 1

Amoxicillin Trihydrate + Clavulanate Potassium 1

Deracoxib 1

Afoxolaner 1

Altrenogest Oily Solution 1

Trenbolone Acet/Estradiol Impl 1

Imidacloprid, Moxidectin 1

Doxycycline 1

Prednisone 1

Melarsomine 1

What to do with this reaction

Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
Browse the full reaction directory to compare report counts across reaction types. All reactions

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Milk production increase (#2308 of 2,481 by report volume); death-coded 13.3%. PlainBreed reaction plate · report volume stamp 15 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →