Reaction profile

The FDA adverse-event record for milk production increase

15 FDA adverse-event reports reference milk production increase (VeDDRA 536). See the species, breeds, and drugs most associated with it below.

15
reports citing this reaction
13.3%
death-coded share
Cattle
most-affected species
Monensin Sodium
most-associated drug
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15
Total Reports
2
Deaths
13.3%
Death Rate

Species Most Affected

Cattle 10
Dog 4
Horse 1

Breeds Most Affected

Holstein-Friesian also known as Holstein 9
Chihuahua 1
Poodle (unspecified) 1
Catahoula Leopard Dog 1
Quarter Horse 1
Hereford cattle 1
Pit Bull 1

Associated Drugs

Monensin Sodium 6
Sometribove Zinc Suspension 4
Sometribove 3
Milbemycin Oxime + Spinosad 1
Amoxicillin Trihydrate + Clavulanate Potassium 1
Deracoxib 1
Afoxolaner 1
Altrenogest Oily Solution 1
Trenbolone Acet/Estradiol Impl 1
Imidacloprid, Moxidectin 1
Doxycycline 1
Prednisone 1
Melarsomine 1

Milk production increase Reaction Insights

15 reports name Milk production increase; 2 recorded a death outcome (13.3% of reported events, not a population-level mortality rate). VeDDRA code: 536.

By species: Cattle (10 reports), Dog (4 reports), Horse (1 reports). By breed: Holstein-Friesian also known as Holstein (9), Chihuahua (1), Poodle (unspecified) (1).

Most co-reported drugs: Monensin Sodium (6 reports), Sometribove Zinc Suspension (4 reports), Sometribove (3 reports), Milbemycin Oxime + Spinosad (1 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.