Reaction profile

The FDA adverse-event record for loss of condition score

169 FDA adverse-event reports reference loss of condition score (VeDDRA 1045). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1128 of 2,481
by report volume (all reactions)
169
reports citing this reaction
33.7%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Loss of condition score has 169 reports now versus 167 in that prior snapshot: 2 more (1.2%).

Report change
+2
Death-coded reports
+1
Death-coded share
+0.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Loss of condition score changes

FDA AER · VeDDRA plate

Code 1045 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 169 reports
  • DEATH-HOT 33.7%
  • MID-PACK #1128/2481
  • PHOTO-FINISH Administration device…
  • SPECIES-DOG Dog · 88
  • DRUG-LEAD Trilostane · 53
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Administration device NOS, damaged (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Report-volume neighbourhood around Loss of condition score

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Administration device… · near169Corneal oedema · near169Inappropriate packagi… · near169Loss of condition sco… · thi…169Not defecating · near169Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Loss of condition score

Loss of condition score: high death-coded share in the FDA AER plate

Signature read: Loss of condition score's 33.7% death-coded share is among the highest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is upper-third: 57 of 169 reports (33.7% of named reports). Nearest volume peer: Administration device NOS, damaged (±0 reports). Lead species Dog (88). Lead co-reported drug Trilostane (53).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 88
Cat 47
Cattle 23
Pig 5
Horse 4
Turkey 1
Sheep 1

Breeds Most Affected

Domestic Shorthair 31
Retriever - Labrador 10
Crossbred Canine/dog 9
Holstein-Friesian also known as Holstein 8
Cattle (unknown) 5
Shepherd Dog - German 5
Terrier - Yorkshire 4
Domestic Longhair 4
Maltese 4
Aberdeen Angus 4

Associated Drugs

Trilostane 53
Bexagliflozin 27
Milbemycin Oxime + Spinosad 13
Gabapentin 11
Maropitant Citrate 10
Enrofloxacin 9
Prednisone 8
Amlodipine 8
Carprofen 7
Grapiprant 6
Monensin Sodium 5
Ractopamine Hydrochloride 5
Spinosad 5
Moxidectin 5
Fluralaner Chew Tablets 5
Rabies Vaccine 5
Midazolam 5
Thiamazole 5
Mirtazapine 5
Insulin 4

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Loss of condition score, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (33.7% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Loss of condition score (#1128 of 2,481 by report volume); death-coded 33.7%. PlainBreed reaction plate · death-coded share stamp 33.7% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →