Rectal haemorrhage

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VeDDRA Code: 271

56 adverse event reports referencing this reaction

56
Total Reports
27
Deaths
4820.0%
Death Rate

Species Most Affected

Dog 50
Cat 5
Human 1

Breeds Most Affected

Retriever - Labrador 5
Crossbred Canine/dog 4
Terrier - Yorkshire 4
Domestic Shorthair 3
Chihuahua 3
Pointer (unspecified) 2
Mixed (Dog) 2
Unknown 2
Collie - Border 2
Retriever - Golden 2

Associated Drugs

Carprofen 11
Maropitant Citrate 8
Polysulfated Glycosaminoglycan 6
Isoflurane 4
Gabapentin 4
Metronidazole 4
Moxidectin 4
Oclacitinib Maleate 4
Fluralaner Chew Tablets 4
Imidacloprid + Moxidectin 3
Selamectin 3
Famotidine 3
Rabies Virus, Kv 3
Fenbendazol Granules 3
Diphenhydramine Hcl 3
Doxycycline 3
Spinosad 2
Propofol 2
Buprenorphine 2
Enrofloxacin 2

Data Summary

Metric Value
Total reports referencing reaction 56
Reports with fatal outcome 27
Case-fatality rate (reported events) 4820.0%
Species observed 3
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 271.

Rectal haemorrhage Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 56 adverse event reports that reference Rectal haemorrhage as a reaction term, including 27 reports with a death outcome — a 4820.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 271, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Rectal haemorrhage appears most frequently in reports for Dog (50 reports), Cat (5 reports), Human (1 reports) — with Dog dominating at 50 entries. Within those species, the breeds most often named alongside this reaction are Retriever - Labrador (5), Crossbred Canine/dog (4), Terrier - Yorkshire (4). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Rectal haemorrhage are Carprofen (11 reports), Maropitant Citrate (8 reports), Polysulfated Glycosaminoglycan (6 reports), Isoflurane (4 reports), with Carprofen appearing alongside this reaction in 11 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial