Bruising

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VeDDRA Code: 1360

1,228 adverse event reports referencing this reaction

1,228
Total Reports
323
Deaths
2630.0%
Death Rate

Species Most Affected

Dog 1,081
Cat 94
Human 36
Cattle 5
Rabbit 5
Pig 3
Horse 2
Turkey 1
Unknown 1

Breeds Most Affected

Retriever - Labrador 86
Chihuahua 68
Crossbred Canine/dog 54
Unknown 44
Retriever - Golden 44
Domestic Shorthair 44
Maltese 42
Terrier - Yorkshire 42
Shih Tzu 40
Dog (unknown) 36

Associated Drugs

Carprofen 192
Maropitant Citrate 139
Moxidectin 98
Tigilanol Tiglate 91
Cefovecin 84
Prednisone 83
Meloxicam 79
Gabapentin 71
Milbemycin Oxime + Spinosad 67
Oclacitinib Maleate 63
Bedinvetmab 61
Buprenorphine 55
Isoflurane 53
Famotidine 51
Propofol 51
Dexamethasone 42
Diphenhydramine 42
Polysulfated Glycosaminoglycan 42
Dexmedetomidine Hydrochloride 41
Enrofloxacin 41

Data Summary

Metric Value
Total reports referencing reaction 1,228
Reports with fatal outcome 323
Case-fatality rate (reported events) 2630.0%
Species observed 9
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 1360.

Bruising Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 1,228 adverse event reports that reference Bruising as a reaction term, including 323 reports with a death outcome — a 2630.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 1360, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Bruising appears most frequently in reports for Dog (1,081 reports), Cat (94 reports), Human (36 reports) — with Dog dominating at 1,081 entries. Within those species, the breeds most often named alongside this reaction are Retriever - Labrador (86), Chihuahua (68), Crossbred Canine/dog (54). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Bruising are Carprofen (192 reports), Maropitant Citrate (139 reports), Moxidectin (98 reports), Tigilanol Tiglate (91 reports), with Carprofen appearing alongside this reaction in 192 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial