Reaction profile

The FDA adverse-event record for bruising

1,288 FDA reports name bruising, a high-volume reaction in the CVM extract (VeDDRA 1360). Plate stamps and neighbourhood peers follow.

#320 of 2,481
by report volume (all reactions)
1,288
reports citing this reaction
25.9%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Bruising has 1,288 reports now versus 1,261 in that prior snapshot: 27 more (2.1%).

Report change
+27
Death-coded reports
+4
Death-coded share
−0.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Bruising changes

FDA AER · VeDDRA plate

Code 1360 VOL-MID

VOL-MID · DEATH-HOT · UPPER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 1,288 reports
  • DEATH-HOT 25.9%
  • UPPER-Q #320/2481
  • PHOTO-FINISH Otitis externa
  • SPECIES-DOG Dog · 1,136
  • DRUG-LEAD Carprofen · 201
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Otitis externa (±1 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Bruising

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Otitis externa · near1289Bruising · this reaction1288Defect Unknown/Not Sp… · near1284Application site infl… · near1270NT - Abnormal necrops… · near1268Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Bruising

Bruising: high death-coded share in the FDA AER plate

Signature read: 333 death-coded reports is a heavy tail count for Bruising in the CVM extract. Report volume is upper-third scale: 1,288 named reports in the openFDA extract. Death-coded share is upper-third: 333 of 1,288 reports (25.9% of named reports). Nearest volume peer: Otitis externa (±1 reports). Lead species Dog (1,136). Lead co-reported drug Carprofen (201).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 1,136
Cat 97
Human 38
Cattle 5
Rabbit 5
Pig 3
Horse 2
Turkey 1
Unknown 1

Breeds Most Affected

Retriever - Labrador 88
Chihuahua 74
Crossbred Canine/dog 58
Retriever - Golden 47
Unknown 46
Domestic Shorthair 46
Terrier - Yorkshire 45
Maltese 44
Shih Tzu 40
Dog (unknown) 37

Associated Drugs

Carprofen 201
Maropitant Citrate 154
Moxidectin 108
Tigilanol Tiglate 104
Prednisone 92
Cefovecin 84
Meloxicam 79
Gabapentin 79
Milbemycin Oxime + Spinosad 67
Bedinvetmab 67
Oclacitinib Maleate 66
Buprenorphine 65
Famotidine 57
Isoflurane 55
Diphenhydramine 55
Propofol 52
Enrofloxacin 46
Dexamethasone 45
Dexmedetomidine Hydrochloride 44
Polysulfated Glycosaminoglycan 43

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Bruising, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (25.9% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Bruising (#320 of 2,481 by report volume); death-coded 25.9%. PlainBreed reaction plate · death-coded report count stamp 333 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →