Emphysema NOS (see 'Respiratory' for pulmonary emphysema)

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VeDDRA Code: 1010

28 adverse event reports referencing this reaction

28
Total Reports
20
Deaths
7140.0%
Death Rate

Species Most Affected

Dog 12
Cat 9
Cattle 6
Human 1

Breeds Most Affected

Domestic (unspecified) 5
Holstein-Friesian also known as Holstein 5
Shih Tzu 3
Shepherd Dog - German 2
Retriever - Labrador 2
Domestic Shorthair 2
Ragdoll 1
Aberdeen Angus 1
Unknown 1
Schnauzer - Miniature 1

Associated Drugs

Meloxicam 3
Fluralaner Chew Tablets 3
Cefovecin Sodium 2
Propofol 2
Carprofen 2
Moxidectin 2
Ivermectin 2
Maropitant Citrate 2
Enrofloxacin 2
Isoflurane 2
Spinosad 2
Prednisone 2
Robenacoxib 2
Dinoprost Tromethamine 2
Ketamine Hydrochloride 1
Dexmedetomidine Hydrochloride 1
Cloprostenol Sodium 1
Ivermectin(1%)/Clorsulon(10%) Injection 1
Recombinant Human Insulin 1
Amoxicillin (As Trihydrate); Clavulanate Potassium ( K-Clavulanate) 1

Data Summary

Metric Value
Total reports referencing reaction 28
Reports with fatal outcome 20
Case-fatality rate (reported events) 7140.0%
Species observed 4
Breeds observed 15
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 1010.

Emphysema NOS (see 'Respiratory' for pulmonary emphysema) Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 28 adverse event reports that reference Emphysema NOS (see 'Respiratory' for pulmonary emphysema) as a reaction term, including 20 reports with a death outcome — a 7140.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 1010, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Emphysema NOS (see 'Respiratory' for pulmonary emphysema) appears most frequently in reports for Dog (12 reports), Cat (9 reports), Cattle (6 reports) — with Dog dominating at 12 entries. Within those species, the breeds most often named alongside this reaction are Domestic (unspecified) (5), Holstein-Friesian also known as Holstein (5), Shih Tzu (3). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Emphysema NOS (see 'Respiratory' for pulmonary emphysema) are Meloxicam (3 reports), Fluralaner Chew Tablets (3 reports), Cefovecin Sodium (2 reports), Propofol (2 reports), with Meloxicam appearing alongside this reaction in 3 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

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Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial