Reaction profile

The FDA adverse-event record for injection site numbness

61 FDA adverse-event reports reference injection site numbness (VeDDRA 1546). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1647 of 2,481
by report volume (all reactions)
61
reports citing this reaction
1.6%
death-coded share
Human
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Injection site numbness has 61 reports now versus 61 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Injection site numbness changes

FDA AER · VeDDRA plate

Code 1546 VOL-LOW

VOL-LOW · DEATH-LOW · MID-PACK · PHOTO-FINISH · SPECIES-HUMAN · DRUG-LEAD · DESK-NARROW · BOOK-FULL

  • VOL-LOW 61 reports
  • DEATH-LOW 1.6%
  • MID-PACK #1647/2481
  • PHOTO-FINISH Intussusception
  • SPECIES-HUMAN Human · 59
  • DRUG-LEAD Maropitant Citrate · 14
  • DESK-NARROW 3 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Intussusception (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Injection site numbness

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Injection site numbne… · thi…61Intussusception · near61Oral pain · near61Paraplegia · near61Retinal haemorrhage · near61Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Injection site numbness

Injection site numbness: low death-coded share in the FDA AER plate

Signature read: 1 death-coded reports is a thin tail count for Injection site numbness in the CVM extract. Report volume sits in the middle third of the reaction corpus. Death-coded share is lower-third: 1 of 61 reports (1.6% of named reports). Nearest volume peer: Intussusception (±0 reports). Lead species Human (59). Lead co-reported drug Maropitant Citrate (14).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Maropitant Citrate appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Human 59
Horse 1
Cat 1

Breeds Most Affected

Unknown 59
Quarter Horse 1
Cat (unknown) 1

Associated Drugs

Maropitant Citrate 14
Pentobarbital Sodium, Phenytoin Sodium 7
Enrofloxacin 5
Tulathromycin 5
Tiletamine Hcl; Zolazapam Hcl 3
Tilmicosin Phosphate 3
Tylosin 2
Eprinomectin 5% Injection 2
Melarsomine Dihydrochloride 2
Moxidectin 2
Imidacloprid + Moxidectin 1
Glycosaminoglycan Polysulfate 1
No Concomitant Products 1
Unspecified Injection 1
Sulfamethoxazole/Trimethoprim 1
Levofloxacin 1
Acetaminophen 1
Ceftiofur Crystalline Free Acid 1
Lisinopril 1
Dexmedetomidine Hydrochloride 1

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Injection site numbness, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (61 here).

Similar death-coded share

Nearest other reactions by death-coded share (1.6% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Injection site numbness (#1647 of 2,481 by report volume); death-coded 1.6%. PlainBreed reaction plate · death-coded report count stamp 1 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →