Reaction profile

The FDA adverse-event record for injection site numbness

58 FDA adverse-event reports reference injection site numbness (VeDDRA 1546). See the species, breeds, and drugs most associated with it below.

58
reports citing this reaction
1.7%
death-coded share
Human
most-affected species
Maropitant Citrate
most-associated drug
Verify with FDA CVM →
58
Total Reports
1
Deaths
1.7%
Death Rate

Species Most Affected

Human 56
Horse 1
Cat 1

Breeds Most Affected

Unknown 56
Quarter Horse 1
Cat (unknown) 1

Associated Drugs

Maropitant Citrate 12
Pentobarbital Sodium, Phenytoin Sodium 7
Enrofloxacin 5
Tulathromycin 5
Tiletamine Hcl; Zolazapam Hcl 3
Tilmicosin Phosphate 3
Tylosin 2
Eprinomectin 5% Injection 2
Melarsomine Dihydrochloride 2
Imidacloprid + Moxidectin 1
Glycosaminoglycan Polysulfate 1
No Concomitant Products 1
Unspecified Injection 1
Sulfamethoxazole/Trimethoprim 1
Levofloxacin 1
Acetaminophen 1
Ceftiofur Crystalline Free Acid 1
Lisinopril 1
Dexmedetomidine Hydrochloride 1
Ivermectin 1

Injection site numbness Reaction Insights

58 reports name Injection site numbness; 1 recorded a death outcome (1.7% of reported events, not a population-level mortality rate). VeDDRA code: 1546.

By species: Human (56 reports), Horse (1 reports), Cat (1 reports). By breed: Unknown (56), Quarter Horse (1), Cat (unknown) (1).

Most co-reported drugs: Maropitant Citrate (12 reports), Pentobarbital Sodium, Phenytoin Sodium (7 reports), Enrofloxacin (5 reports), Tulathromycin (5 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.