INEFFECTIVE, ANTIEMETIC

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VeDDRA Code: 99085

521 adverse event reports referencing this reaction

521
Total Reports
58
Deaths
1110.0%
Death Rate

Species Most Affected

Dog 439
Cat 81
Other 1

Breeds Most Affected

Retriever - Labrador 48
Crossbred Canine/dog 40
Domestic Shorthair 28
Dog (unknown) 27
Terrier - Yorkshire 24
Retriever - Golden 20
Domestic (unspecified) 18
Boxer (German Boxer) 15
Cat (unknown) 14
Bichon Frise 12

Associated Drugs

Maropitant Citrate 404
Maropitant 159
Carprofen 35
Famotidine 34
Moxidectin 29
Canine Adenovirus Type 2, Strain Manhattan, 12-13-76; Canine Distemper Virus, St 27
Metronidazole 23
Cefovecin 19
Sucralfate 15
Rabies Virus, Kv 14
Anesthetic 13
Dexamethasone 12
Selamectin 12
Leptospira Canicola L-15 Strain C-51;Leptospira Grippotyphosa 1550 Lot 10005 Str 12
Enrofloxacin 11
Diphenhydramine Hcl 11
Prednisone 9
Buprenorphine 8
Sam-E, Silybin, Vitamin E, Zinc 8
Ampicillin 8

Data Summary

Metric Value
Total reports referencing reaction 521
Reports with fatal outcome 58
Case-fatality rate (reported events) 1110.0%
Species observed 3
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 99085.

INEFFECTIVE, ANTIEMETIC Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 521 adverse event reports that reference INEFFECTIVE, ANTIEMETIC as a reaction term, including 58 reports with a death outcome — a 1110.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 99085, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

INEFFECTIVE, ANTIEMETIC appears most frequently in reports for Dog (439 reports), Cat (81 reports), Other (1 reports) — with Dog dominating at 439 entries. Within those species, the breeds most often named alongside this reaction are Retriever - Labrador (48), Crossbred Canine/dog (40), Domestic Shorthair (28). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with INEFFECTIVE, ANTIEMETIC are Maropitant Citrate (404 reports), Maropitant (159 reports), Carprofen (35 reports), Famotidine (34 reports), with Maropitant Citrate appearing alongside this reaction in 404 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial