Reaction profile

The FDA adverse-event record for ineffective, antiemetic

524 FDA reports name ineffective, antiemetic, a high-volume reaction in the CVM extract (VeDDRA 99085). Plate stamps and neighbourhood peers follow.

#630 of 2,481
by report volume (all reactions)
524
reports citing this reaction
11.1%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. INEFFECTIVE, ANTIEMETIC has 524 reports now versus 522 in that prior snapshot: 2 more (0.4%).

Report change
+2
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to INEFFECTIVE, ANTIEMETIC changes

FDA AER · VeDDRA plate

Code 99085 VOL-MID

VOL-MID · DEATH-ELEV · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 524 reports
  • DEATH-ELEV 11.1%
  • MID-PACK #630/2481
  • PHOTO-FINISH Collapse of leg
  • SPECIES-DOG Dog · 441
  • DRUG-LEAD Maropitant Citrate · 408
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Collapse of leg (±0 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around INEFFECTIVE, ANTIEMETIC

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Barking · near527Rolling · near525Collapse of leg · near524INEFFECTIVE, ANTIEMET… · thi…524Hyposthenuria · near523Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around INEFFECTIVE, ANTIEMETIC

What the FDA AER plate says about INEFFECTIVE, ANTIEMETIC

Signature read: 524 reports place INEFFECTIVE, ANTIEMETIC in the upper third of FDA AER volume (#630 of 2,481). Report volume is upper-third scale: 524 named reports in the openFDA extract. 58 of 524 reports were death-coded (11.1% of named reports, not a population mortality rate). Nearest volume peer: Collapse of leg (±0 reports). Lead species Dog (441). Lead co-reported drug Maropitant Citrate (408).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Maropitant Citrate appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 441
Cat 82
Other 1

Breeds Most Affected

Retriever - Labrador 48
Crossbred Canine/dog 40
Domestic Shorthair 29
Dog (unknown) 27
Terrier - Yorkshire 24
Retriever - Golden 20
Domestic (unspecified) 18
Boxer (German Boxer) 15
Cat (unknown) 14
Terrier - Bull - American Pit 13

Associated Drugs

Maropitant Citrate 408
Maropitant 159
Famotidine 35
Carprofen 35
Moxidectin 29
Canine Adenovirus Type 2, Strain Manhattan, 12-13-76; Canine Distemper Virus, St 27
Metronidazole 23
Cefovecin 19
Sucralfate 16
Rabies Virus, Kv 14
Anesthetic 13
Dexamethasone 12
Selamectin 12
Leptospira Canicola L-15 Strain C-51;Leptospira Grippotyphosa 1550 Lot 10005 Str 12
Enrofloxacin 11
Diphenhydramine Hcl 11
Gabapentin 10
Prednisone 9
Metoclopramide 9
Ampicillin 8

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for INEFFECTIVE, ANTIEMETIC, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (524 here).

Similar death-coded share

Nearest other reactions by death-coded share (11.1% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for INEFFECTIVE, ANTIEMETIC (#630 of 2,481 by report volume); death-coded 11.1%. PlainBreed reaction plate · report volume stamp 524 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →