Reaction profile

The FDA adverse-event record for ineffective, antiemetic

521 FDA adverse-event reports reference ineffective, antiemetic (VeDDRA 99085). See the species, breeds, and drugs most associated with it below.

521
reports citing this reaction
11.1%
death-coded share
Dog
most-affected species
Maropitant Citrate
most-associated drug
Verify with FDA CVM →
521
Total Reports
58
Deaths
11.1%
Death Rate

Species Most Affected

Dog 439
Cat 81
Other 1

Breeds Most Affected

Retriever - Labrador 48
Crossbred Canine/dog 40
Domestic Shorthair 28
Dog (unknown) 27
Terrier - Yorkshire 24
Retriever - Golden 20
Domestic (unspecified) 18
Boxer (German Boxer) 15
Cat (unknown) 14
Bichon Frise 12

Associated Drugs

Maropitant Citrate 404
Maropitant 159
Carprofen 35
Famotidine 34
Moxidectin 29
Canine Adenovirus Type 2, Strain Manhattan, 12-13-76; Canine Distemper Virus, St 27
Metronidazole 23
Cefovecin 19
Sucralfate 15
Rabies Virus, Kv 14
Anesthetic 13
Dexamethasone 12
Selamectin 12
Leptospira Canicola L-15 Strain C-51;Leptospira Grippotyphosa 1550 Lot 10005 Str 12
Enrofloxacin 11
Diphenhydramine Hcl 11
Prednisone 9
Buprenorphine 8
Sam-E, Silybin, Vitamin E, Zinc 8
Ampicillin 8

INEFFECTIVE, ANTIEMETIC Reaction Insights

521 reports name INEFFECTIVE, ANTIEMETIC; 58 recorded a death outcome (11.1% of reported events, not a population-level mortality rate). VeDDRA code: 99085.

By species: Dog (439 reports), Cat (81 reports), Other (1 reports). By breed: Retriever - Labrador (48), Crossbred Canine/dog (40), Domestic Shorthair (28).

Most co-reported drugs: Maropitant Citrate (404 reports), Maropitant (159 reports), Carprofen (35 reports), Famotidine (34 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.