Reaction profile

The FDA adverse-event record for decreased blood urea nitrogen (bun) or creatinine

174 FDA adverse-event reports reference decreased blood urea nitrogen (bun) or creatinine (VeDDRA 2702). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1111 of 2,481
by report volume (all reactions)
174
reports citing this reaction
24.1%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Decreased blood urea nitrogen (BUN) or creatinine has 174 reports now versus 169 in that prior snapshot: 5 more (3.0%).

Report change
+5
Death-coded reports
+2
Death-coded share
+0.5 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Decreased blood urea nitrogen (BUN) or creatinine changes

FDA AER · VeDDRA plate

Code 2702 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 174 reports
  • DEATH-HOT 24.1%
  • MID-PACK #1111/2481
  • PHOTO-FINISH Cough, productive
  • SPECIES-DOG Dog · 96
  • DRUG-LEAD Maropitant Citrate · 24
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Cough, productive (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Decreased blood urea nitrogen or creatinine

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Elevated lactate · near175Cough, productive · near174Decreased blood urea… · this…174Paraparesis · near174Angioedema · near173Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Decreased blood urea nitrogen (BUN) or creatinine

What the FDA AER plate says about Decreased blood urea nitrogen (BUN) or creatinine

Signature read: 42 death-coded reports is a heavy tail count for Decreased blood urea nitrogen (BUN) or creatinine in the CVM extract. Report volume sits in the middle third of the reaction corpus. 42 of 174 reports were death-coded (24.1% of named reports, not a population mortality rate). Nearest volume peer: Cough, productive (±0 reports). Lead species Dog (96). Lead co-reported drug Maropitant Citrate (24).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Maropitant Citrate appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 96
Cat 74
Horse 2
Cattle 1
Goat 1

Breeds Most Affected

Domestic Shorthair 54
Retriever - Labrador 11
Retriever - Golden 9
Boxer (German Boxer) 8
Domestic Mediumhair 7
Chihuahua 6
Cat (unknown) 6
Crossbred Canine/dog 4
Shepherd Dog - Australian 3
Cat (other) 3

Associated Drugs

Maropitant Citrate 24
Gabapentin 21
Cefovecin 16
Carprofen 15
Buprenorphine 13
Bedinvetmab 13
Robenacoxib 11
Velagliflozin Proline Monohydrate 11
Pyrantel Pamoate;Sarolaner 10
Moxidectin 8
Afoxolaner 7
Ondansetron 7
Eprinomectin + Esafoxolaner + Praziquantel 7
Metronidazole 6
Selamectin;Sarolaner 6
Fluralaner Spot-On Solution 6
Meloxicam 6
Propofol 6
Enrofloxacin 6
Cefovecin Sodium 5

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Decreased blood urea nitrogen (BUN) or creatinine, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (174 here).

Similar death-coded share

Nearest other reactions by death-coded share (24.1% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Decreased blood urea nitrogen (BUN) or creatinine (#1111 of 2,481 by report volume); death-coded 24.1%. PlainBreed reaction plate · death-coded report count stamp 42 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →