Reaction profile

The FDA adverse-event record for pemphigus foliaceus

91 FDA adverse-event reports reference pemphigus foliaceus (VeDDRA 1225). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1440 of 2,481
by report volume (all reactions)
91
reports citing this reaction
16.5%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Pemphigus foliaceus has 91 reports now versus 90 in that prior snapshot: 1 more (1.1%).

Report change
+1
Death-coded reports
+0
Death-coded share
−0.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Pemphigus foliaceus changes

FDA AER · VeDDRA plate

Code 1225 VOL-LOW

VOL-LOW · DEATH-ELEV · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 91 reports
  • DEATH-ELEV 16.5%
  • MID-PACK #1440/2481
  • PHOTO-FINISH Application site pyod…
  • SPECIES-DOG Dog · 69
  • DRUG-LEAD Prednisone · 13
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Application site pyoderma (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Pemphigus foliaceus

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Application site pyod… · near91Gastric volvulus · near91Pemphigus foliaceus · this r…91Rough recovery · near91Sensory abnormality N… · near91Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Pemphigus foliaceus

What the FDA AER plate says about Pemphigus foliaceus

Signature read: report volume at 91 (#1440 of 2,481) is the standout scale stamp on Pemphigus foliaceus. Report volume sits in the middle third of the reaction corpus. 15 of 91 reports were death-coded (16.5% of named reports, not a population mortality rate). Nearest volume peer: Application site pyoderma (±0 reports). Lead species Dog (69). Lead co-reported drug Prednisone (13).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Prednisone appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 69
Cat 21
Horse 1

Breeds Most Affected

Domestic Shorthair 13
Retriever - Labrador 10
Retriever - Golden 6
Crossbred Canine/dog 5
Dog (unknown) 4
Dachshund (unspecified) 3
Terrier - Boston 3
Spaniel - Cocker American 3
Domestic Mediumhair 3
Pit Bull 2

Associated Drugs

Prednisone 13
Cefovecin 12
Oclacitinib Maleate 11
Buprenorphine 11
Afoxolaner 10
Prednisolone 8
Cefpodoxime Proxetil 8
Gabapentin 8
Moxidectin 7
Ivermectin + Pyrantel As Pamoate Salt 6
Fipronil 9.8%/S-Methoprene 8.8%/ Amitraz 22.1% Spot-On 6
Carprofen 6
Cyclosporine 6
Maropitant Citrate 6
Medicated Shampoo 6
Propofol 6
Isoflurane 6
Robenacoxib 6
Tramadol 5
Cephalexin 5

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Pemphigus foliaceus, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (91 here).

Similar death-coded share

Nearest other reactions by death-coded share (16.5% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Pemphigus foliaceus (#1440 of 2,481 by report volume); death-coded 16.5%. PlainBreed reaction plate · report volume stamp 91 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →