Reaction profile

The FDA adverse-event record for pemphigus foliaceus

89 FDA adverse-event reports reference pemphigus foliaceus (VeDDRA 1225). See the species, breeds, and drugs most associated with it below.

89
reports citing this reaction
16.9%
death-coded share
Dog
most-affected species
Prednisone
most-associated drug
Verify with FDA CVM →
89
Total Reports
15
Deaths
16.9%
Death Rate

Species Most Affected

Dog 68
Cat 20
Horse 1

Breeds Most Affected

Domestic Shorthair 12
Retriever - Labrador 10
Retriever - Golden 6
Crossbred Canine/dog 5
Dog (unknown) 4
Dachshund (unspecified) 3
Terrier - Boston 3
Spaniel - Cocker American 3
Domestic Mediumhair 3
Pit Bull 2

Associated Drugs

Prednisone 13
Cefovecin 12
Buprenorphine 11
Oclacitinib Maleate 10
Afoxolaner 10
Prednisolone 8
Cefpodoxime Proxetil 8
Gabapentin 8
Moxidectin 7
Ivermectin + Pyrantel As Pamoate Salt 6
Fipronil 9.8%/S-Methoprene 8.8%/ Amitraz 22.1% Spot-On 6
Cyclosporine 6
Maropitant Citrate 6
Medicated Shampoo 6
Propofol 6
Isoflurane 6
Robenacoxib 6
Tramadol 5
Cephalexin 5
Carprofen 5

Pemphigus foliaceus Reaction Insights

89 reports name Pemphigus foliaceus; 15 recorded a death outcome (16.9% of reported events, not a population-level mortality rate). VeDDRA code: 1225.

By species: Dog (68 reports), Cat (20 reports), Horse (1 reports). By breed: Domestic Shorthair (12), Retriever - Labrador (10), Retriever - Golden (6).

Most co-reported drugs: Prednisone (13 reports), Cefovecin (12 reports), Buprenorphine (11 reports), Oclacitinib Maleate (10 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.