Rubra

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VeDDRA Code: 947

26 adverse event reports referencing this reaction

26
Total Reports
0
Deaths
0.0%
Death Rate

Species Most Affected

Cattle 23
Dog 2
Horse 1

Breeds Most Affected

Cattle (other) 6
Aberdeen Angus 5
Crossbred Bovine/Cattle 4
Unknown 4
Cattle (unknown) 2
Charolais 2
Alaskan Malamute 1
Morgan 1
Pit Bull 1

Associated Drugs

Ivermectin 0.5% Pour-On Topical Solution 23
Afoxolaner 28.3 Mg Chewable Tablets 1
Afoxolaner 136 Mg Chewable Tablets 1
Ivermectin(1.55%)/Praziquantel(7.75%) Paste 1
Milbemycin Oxime 1

Data Summary

Metric Value
Total reports referencing reaction 26
Reports with fatal outcome 0
Case-fatality rate (reported events) 0.0%
Species observed 3
Breeds observed 9
Drugs associated with reaction 5

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 947.

Rubra Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 26 adverse event reports that reference Rubra as a reaction term, including 0 reports with a death outcome — a 0.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 947, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Rubra appears most frequently in reports for Cattle (23 reports), Dog (2 reports), Horse (1 reports) — with Cattle dominating at 23 entries. Within those species, the breeds most often named alongside this reaction are Cattle (other) (6), Aberdeen Angus (5), Crossbred Bovine/Cattle (4). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Rubra are Ivermectin 0.5% Pour-On Topical Solution (23 reports), Afoxolaner 28.3 Mg Chewable Tablets (1 reports), Afoxolaner 136 Mg Chewable Tablets (1 reports), Ivermectin(1.55%)/Praziquantel(7.75%) Paste (1 reports), with Ivermectin 0.5% Pour-On Topical Solution appearing alongside this reaction in 23 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial