Reaction profile

The FDA adverse-event record for rubra

26 FDA adverse-event reports reference rubra (VeDDRA 947). See the species, breeds, and drugs most associated with it below.

26
reports citing this reaction
0.0%
death-coded share
Cattle
most-affected species
Ivermectin 0.5% Pour-On Topical Solution
most-associated drug
Verify with FDA CVM →
26
Total Reports
0
Deaths
0.0%
Death Rate

Species Most Affected

Cattle 23
Dog 2
Horse 1

Breeds Most Affected

Cattle (other) 6
Aberdeen Angus 5
Crossbred Bovine/Cattle 4
Unknown 4
Cattle (unknown) 2
Charolais 2
Alaskan Malamute 1
Morgan 1
Pit Bull 1

Associated Drugs

Ivermectin 0.5% Pour-On Topical Solution 23
Afoxolaner 28.3 Mg Chewable Tablets 1
Afoxolaner 136 Mg Chewable Tablets 1
Ivermectin(1.55%)/Praziquantel(7.75%) Paste 1
Milbemycin Oxime 1

Rubra Reaction Insights

26 reports name Rubra; 0 recorded a death outcome (0.0% of reported events, not a population-level mortality rate). VeDDRA code: 947.

By species: Cattle (23 reports), Dog (2 reports), Horse (1 reports). By breed: Cattle (other) (6), Aberdeen Angus (5), Crossbred Bovine/Cattle (4).

Most co-reported drugs: Ivermectin 0.5% Pour-On Topical Solution (23 reports), Afoxolaner 28.3 Mg Chewable Tablets (1 reports), Afoxolaner 136 Mg Chewable Tablets (1 reports), Ivermectin(1.55%)/Praziquantel(7.75%) Paste (1 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.