Reaction profile

The FDA adverse-event record for reluctant to move

3,904 FDA adverse-event reports reference reluctant to move (VeDDRA 1025). See the species, breeds, and drugs most associated with it below.

3,904
reports citing this reaction
18.9%
death-coded share
Dog
most-affected species
Milbemycin Oxime + Spinosad
most-associated drug
Verify with FDA CVM →
3,904
Total Reports
737
Deaths
18.9%
Death Rate

Species Most Affected

Dog 3,156
Cat 569
Horse 97
Cattle 45
Pig 8
Turkey 4
Rabbit 4
Chicken 4
Goat 2
Rat 2

Breeds Most Affected

Domestic Shorthair 323
Crossbred Canine/dog 306
Retriever - Labrador 292
Chihuahua 143
Retriever - Golden 139
Shepherd Dog - German 119
Shih Tzu 110
Boxer (German Boxer) 109
Dog (unknown) 100
Terrier - Yorkshire 97

Associated Drugs

Milbemycin Oxime + Spinosad 444
Carprofen 285
Bedinvetmab 246
Maropitant Citrate 197
Spinosad 186
Gabapentin 170
Moxidectin 157
Afoxolaner 150
Trilostane 144
Fluralaner 13.64% 12-Week Chew 136
Fluralaner Chew Tablets 129
Prednisone 110
Buprenorphine 107
Cefovecin 104
Oclacitinib Maleate 101
Pyrantel Pamoate;Sarolaner 95
Meloxicam 92
Melarsomine Dihydrochloride 90
Selamectin 90
Ivermectin + Pyrantel As Pamoate Salt 87

Reluctant to move Reaction Insights

3,904 reports name Reluctant to move; 737 recorded a death outcome (18.9% of reported events, not a population-level mortality rate). VeDDRA code: 1025.

By species: Dog (3,156 reports), Cat (569 reports), Horse (97 reports). By breed: Domestic Shorthair (323), Crossbred Canine/dog (306), Retriever - Labrador (292).

Most co-reported drugs: Milbemycin Oxime + Spinosad (444 reports), Carprofen (285 reports), Bedinvetmab (246 reports), Maropitant Citrate (197 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.