Reaction profile

The FDA adverse-event record for local erythema

233 FDA adverse-event reports reference local erythema (VeDDRA 3129). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#970 of 2,481
by report volume (all reactions)
233
reports citing this reaction
4.3%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Local erythema has 233 reports now versus 202 in that prior snapshot: 31 more (15.3%).

Report change
+31
Death-coded reports
+2
Death-coded share
+0.3 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Local erythema changes

FDA AER · VeDDRA plate

Code 3129 VOL-LOW

VOL-LOW · DEATH-LOW · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 233 reports
  • DEATH-LOW 4.3%
  • MID-PACK #970/2481
  • PHOTO-FINISH Lack of coordination…
  • SPECIES-DOG Dog · 176
  • DRUG-LEAD Frunevetmab · 36
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Lack of coordination (see also 'Ear' - vestibular disorder) (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Local erythema

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Brain disorder NOS · near234Metastatic neoplasia · near234Lack of coordination… · near233Local erythema · this reacti…233Ulcerative dermatitis · near233Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Local erythema

Local erythema: low death-coded share in the FDA AER plate

Signature read: Local erythema's 4.3% death-coded share is among the lowest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is lower-third: 10 of 233 reports (4.3% of named reports). Nearest volume peer: Lack of coordination (see also 'Ear' - vestibular disorder) (±0 reports). Lead species Dog (176). Lead co-reported drug Frunevetmab (36).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Frunevetmab appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 176
Cat 54
Human 3

Breeds Most Affected

Domestic Shorthair 40
Retriever - Labrador 13
Terrier - Bull - American Pit 12
Bulldog - French 12
Dachshund (unspecified) 11
Crossbred Canine/dog 11
Shepherd Dog - German 7
Shepherd Dog - Australian 6
Pit Bull 6
Retriever - Golden 6

Associated Drugs

Frunevetmab 36
Oclacitinib Maleate 29
Bedinvetmab 28
Gabapentin 27
Diphenhydramine 26
Maropitant Citrate 23
Moxidectin 22
Prednisone 21
Tigilanol Tiglate 20
Carprofen 16
Anti-Il31 Mab Mcs Lot #1283563 16
Famotidine 14
Cefovecin 12
Buprenorphine 12
Pyrantel Pamoate;Sarolaner 11
Butorphanol 11
Rabies Virus, Kv 10
Unspecified 10
Selamectin;Sarolaner 9
Cyclosporine 9

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Local erythema, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (4.3% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Local erythema (#970 of 2,481 by report volume); death-coded 4.3%. PlainBreed reaction plate · death-coded share stamp 4.3% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →