Reaction profile

The FDA adverse-event record for palpebral disorder nos

190 FDA adverse-event reports reference palpebral disorder nos (VeDDRA 426). See the species, breeds, and drugs most associated with it below.

190
reports citing this reaction
18.4%
death-coded share
Dog
most-affected species
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride
most-associated drug
Verify with FDA CVM →
190
Total Reports
35
Deaths
18.4%
Death Rate

Species Most Affected

Dog 165
Cat 22
Human 2
Horse 1

Breeds Most Affected

Boxer (German Boxer) 14
Domestic Shorthair 12
Retriever - Golden 8
Retriever - Labrador 8
Chihuahua 7
Terrier - Bull - American Pit 7
Bulldog - French 7
Spaniel - King Charles Cavalier 6
Terrier - Yorkshire 5
Poodle - Miniature 5

Associated Drugs

Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 33
Milbemycin Oxime + Spinosad 21
Spinosad 18
Carprofen 18
Maropitant Citrate 18
Trilostane 13
Bedinvetmab 12
Buprenorphine 10
Pilocarpine 10
Prednisone 9
Eye Lubricant 7
Meloxicam 6
Gabapentin 6
Propofol 6
Enrofloxacin 6
Ivermectin 5
Cyclosporine A 5
Dexmedetomidine Hydrochloride 5
Selamectin 5
Marbofloxacin 5

Palpebral disorder NOS Reaction Insights

190 reports name Palpebral disorder NOS; 35 recorded a death outcome (18.4% of reported events, not a population-level mortality rate). VeDDRA code: 426.

By species: Dog (165 reports), Cat (22 reports), Human (2 reports). By breed: Boxer (German Boxer) (14), Domestic Shorthair (12), Retriever - Golden (8).

Most co-reported drugs: Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride (33 reports), Milbemycin Oxime + Spinosad (21 reports), Spinosad (18 reports), Carprofen (18 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.