Reaction profile

The FDA adverse-event record for elevated mean corpuscular haemoglobin concentration (mchc)

83 FDA adverse-event reports reference elevated mean corpuscular haemoglobin concentration (mchc) (VeDDRA 3091). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1483 of 2,481
by report volume (all reactions)
83
reports citing this reaction
14.5%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Elevated mean corpuscular haemoglobin concentration (MCHC) has 83 reports now versus 75 in that prior snapshot: 8 more (10.7%).

Report change
+8
Death-coded reports
+0
Death-coded share
−1.5 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Elevated mean corpuscular haemoglobin concentration (MCHC) changes

FDA AER · VeDDRA plate

Code 3091 VOL-LOW

VOL-LOW · DEATH-ELEV · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 83 reports
  • DEATH-ELEV 14.5%
  • MID-PACK #1483/2481
  • PHOTO-FINISH Destructive behaviour
  • SPECIES-DOG Dog · 59
  • DRUG-LEAD Gabapentin · 16
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Destructive behaviour (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Elevated mean corpuscular haemoglobin concentr…

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Destructive behaviour · near83Elevated mean corpusc… · thi…83Erosion · near83Haemoglobinuria · near83Injection site scratc… · near83Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Elevated mean corpuscular haemoglobin concentration (MCHC)

What the FDA AER plate says about Elevated mean corpuscular haemoglobin concentration (MCHC)

Signature read: report volume at 83 (#1483 of 2,481) is the standout scale stamp on Elevated mean corpuscular haemoglobin concentration (MCHC). Report volume sits in the middle third of the reaction corpus. 12 of 83 reports were death-coded (14.5% of named reports, not a population mortality rate). Nearest volume peer: Destructive behaviour (±0 reports). Lead species Dog (59). Lead co-reported drug Gabapentin (16).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Gabapentin appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 59
Cat 24

Breeds Most Affected

Domestic Shorthair 17
Retriever - Labrador 11
Retriever - Golden 4
Boxer (German Boxer) 4
Domestic Longhair 3
Bulldog - English 3
Dog (unknown) 2
Collie - Border 2
Persian 2
Terrier - Yorkshire 2

Associated Drugs

Gabapentin 16
Carprofen 16
Maropitant Citrate 12
Afoxolaner 8
Bedinvetmab 8
Bexagliflozin 7
Isoflurane 6
Prednisone 6
Sucralfate 5
Moxidectin 5
Doxycycline 4
Buprenorphine 4
Enrofloxacin 4
Maropitant 4
Capromorelin 4
Metronidazole 4
Fluralaner 4
Eprinomectin + Esafoxolaner + Praziquantel 4
Milbemycin Oxime + Praziquantel 4
Lotilaner 4

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Elevated mean corpuscular haemoglobin concentration (MCHC), both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (83 here).

Similar death-coded share

Nearest other reactions by death-coded share (14.5% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Elevated mean corpuscular haemoglobin concentration (MCHC) (#1483 of 2,481 by report volume); death-coded 14.5%. PlainBreed reaction plate · report volume stamp 83 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →