Reaction profile

The FDA adverse-event record for surgical site haemorrhage

50 FDA adverse-event reports reference surgical site haemorrhage (VeDDRA 2280). See the species, breeds, and drugs most associated with it below.

50
reports citing this reaction
30.0%
death-coded share
Dog
most-affected species
Unspecified
most-associated drug
Verify with FDA CVM →
50
Total Reports
15
Deaths
30.0%
Death Rate

Species Most Affected

Dog 30
Cat 16
Other Birds 3
Cattle 1

Breeds Most Affected

Domestic Shorthair 9
Dog (unknown) 5
Mixed (Dog) 3
Retriever - Labrador 3
Domestic Longhair 3
Pit Bull 2
Retriever - Golden 2
Siamese 2
Other Birds (other) 2
Dachshund (unspecified) 1

Associated Drugs

Unspecified 17
Isoflurane 12
Robenacoxib 11
Butorphanol 10
Ketamine 9
Dexmedetomidine 9
Carprofen 6
Buprenorphine 5
Meloxicam 4
Propofol 4
Dexmedetomidine Hydrochloride 3
Deracoxib 3
Polysulfated Glycosaminoglycan 3
Sevoflurane 3
Anesthetic 3
Fluralaner 13.64% 12-Week Chew 3
Cefovecin 2
Atipamezole Hydrochloride 2
Tramadol 2
Butorphanol Tartrate 2

Surgical site haemorrhage Reaction Insights

50 reports name Surgical site haemorrhage; 15 recorded a death outcome (30.0% of reported events, not a population-level mortality rate). VeDDRA code: 2280.

By species: Dog (30 reports), Cat (16 reports), Other Birds (3 reports). By breed: Domestic Shorthair (9), Dog (unknown) (5), Mixed (Dog) (3).

Most co-reported drugs: Unspecified (17 reports), Isoflurane (12 reports), Robenacoxib (11 reports), Butorphanol (10 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.