Reaction profile

The FDA adverse-event record for hypertrophic concentric cardiomyopathy

25 FDA adverse-event reports reference hypertrophic concentric cardiomyopathy (VeDDRA 2301). See the species, breeds, and drugs most associated with it below.

25
reports citing this reaction
72.0%
death-coded share
Cat
most-affected species
Frunevetmab
most-associated drug
Verify with FDA CVM →
25
Total Reports
18
Deaths
72.0%
Death Rate

Species Most Affected

Cat 22
Dog 3

Breeds Most Affected

Domestic Shorthair 13
Maine Coon 3
Domestic Mediumhair 2
Cat (other) 2
Burmese 1
Spitz - German Pomeranian 1
Chihuahua 1
Domestic Longhair 1
Corgi (unspecified) 1

Associated Drugs

Frunevetmab 8
Buprenorphine 6
Prednisolone 4
Maropitant Citrate 3
Meloxicam 3
Doxycycline 3
Fluralaner 13.64% 12-Week Chew 2
Cefovecin 2
Bexagliflozin 2
Enrofloxacin 2
Hydrotherapy 2
Dexmedetomidine Hydrochloride 1
Atipamezole Hydrochloride 1
Feline Distemper Combination 1
Methylprednisone 1
Eprinomectin + Praziquantel 1
Purevax Feline Rabies - 1901.R1 1
Fluralaner Spot-On Solution 1
Milbemycin/Lufenuron Tablets 1
Water, Sodium Chloride 1

Hypertrophic concentric cardiomyopathy Reaction Insights

25 reports name Hypertrophic concentric cardiomyopathy; 18 recorded a death outcome (72.0% of reported events, not a population-level mortality rate). VeDDRA code: 2301.

By species: Cat (22 reports), Dog (3 reports). By breed: Domestic Shorthair (13), Maine Coon (3), Domestic Mediumhair (2).

Most co-reported drugs: Frunevetmab (8 reports), Buprenorphine (6 reports), Prednisolone (4 reports), Maropitant Citrate (3 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.