Reaction profile

The FDA adverse-event record for hypertrophic concentric cardiomyopathy

33 FDA reports name hypertrophic concentric cardiomyopathy, a lower-volume reaction in the CVM extract (VeDDRA 2301). Plate stamps and neighbourhood peers follow.

#1942 of 2,481
by report volume (all reactions)
33
reports citing this reaction
69.7%
death-coded share
Cat
most-affected species
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Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Hypertrophic concentric cardiomyopathy has 33 reports now versus 29 in that prior snapshot: 4 more (13.8%).

Report change
+4
Death-coded reports
+3
Death-coded share
+0.7 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Hypertrophic concentric cardiomyopathy changes

FDA AER · VeDDRA plate

Code 2301 VOL-TRACE

VOL-TRACE · DEATH-HOT · LOWER-Q · PHOTO-FINISH · SPECIES-CAT · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 33 reports
  • DEATH-HOT 69.7%
  • LOWER-Q #1942/2481
  • PHOTO-FINISH Abnormal dexamethason…
  • SPECIES-CAT Cat · 29
  • DRUG-LEAD Frunevetmab · 12
  • DESK-WIDE 11 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Abnormal dexamethasone suppression test (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around Hypertrophic concentric cardiomyopathy

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Abnormal dexamethason… · near33Burning mouth sensati… · near33Decreased number of s… · near33Displaced abomasum · near33Hypertrophic concentr… · thi…33Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Hypertrophic concentric cardiomyopathy

Hypertrophic concentric cardiomyopathy: high death-coded share in the FDA AER plate

Signature read: Hypertrophic concentric cardiomyopathy's 69.7% death-coded share is among the highest in the openFDA reaction corpus. Report volume is lower-third scale: 33 named reports in the openFDA extract. Death-coded share is upper-third: 23 of 33 reports (69.7% of named reports). Nearest volume peer: Abnormal dexamethasone suppression test (±0 reports). Lead species Cat (29). Lead co-reported drug Frunevetmab (12).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Cat 29
Dog 4

Breeds Most Affected

Domestic Shorthair 17
Maine Coon 3
Domestic Mediumhair 3
Domestic Longhair 2
Cat (other) 2
Burmese 1
Chihuahua 1
Spitz - German Pomeranian 1
Corgi (unspecified) 1
Crossbred Canine/dog 1

Associated Drugs

Frunevetmab 12
Buprenorphine 7
Maropitant Citrate 6
Prednisolone 4
Doxycycline 3
Meloxicam 3
Bexagliflozin 3
Furosemide 3
Pimobendan 3
Fluralaner 13.64% 12-Week Chew 2
Cefovecin 2
Enrofloxacin 2
Hydrotherapy 2
Maropitant 2
Gabapentin 2
Clopidogrel 2
Robenacoxib 2
Fluids 2
Appetite Stimulant 2
Prescription Diet 2

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Hypertrophic concentric cardiomyopathy (#1942 of 2,481 by report volume); death-coded 69.7%. PlainBreed reaction plate · death-coded share stamp 69.7% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →