Reaction profile

The FDA adverse-event record for flatulence, bloating and distension

126 FDA adverse-event reports reference flatulence, bloating and distension (VeDDRA 1477). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1281 of 2,481
by report volume (all reactions)
126
reports citing this reaction
16.7%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Flatulence, bloating and distension has 126 reports now versus 124 in that prior snapshot: 2 more (1.6%).

Report change
+2
Death-coded reports
+0
Death-coded share
−0.3 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Flatulence, bloating and distension changes

FDA AER · VeDDRA plate

Code 1477 VOL-LOW

VOL-LOW · DEATH-ELEV · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 126 reports
  • DEATH-ELEV 16.7%
  • MID-PACK #1281/2481
  • PHOTO-FINISH Extensor rigidity
  • SPECIES-DOG Dog · 97
  • DRUG-LEAD Trilostane · 15
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Extensor rigidity (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Flatulence, bloating and distension

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Extensor rigidity · near126Flatulence, bloating… · this…126Hiccup · near126Infertility NOS · near126Large platelets · near126Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Flatulence, bloating and distension

What the FDA AER plate says about Flatulence, bloating and distension

Signature read: 21 death-coded reports is the most distinctive absolute-outcome stamp on Flatulence, bloating and distension. Report volume sits in the middle third of the reaction corpus. 21 of 126 reports were death-coded (16.7% of named reports, not a population mortality rate). Nearest volume peer: Extensor rigidity (±0 reports). Lead species Dog (97). Lead co-reported drug Trilostane (15).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Trilostane appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 97
Cat 15
Horse 5
Cattle 5
Human 3
Unknown 1

Breeds Most Affected

Retriever - Labrador 14
Domestic Shorthair 5
Beagle 5
Shih Tzu 4
Unknown 4
Crossbred Canine/dog 4
Shepherd Dog - German 4
Cattle (unknown) 4
Boxer (German Boxer) 3
Terrier - Yorkshire 3

Associated Drugs

Trilostane 15
Carprofen 12
Maropitant Citrate 11
Milbemycin Oxime + Spinosad 9
Afoxolaner 9
Ivermectin + Pyrantel As Pamoate Salt 8
Gabapentin 7
Fluralaner Chew Tablets 6
Metronidazole 5
Vaccines (Unknown) 5
Cefovecin 5
Monensin Sodium 5
Oclacitinib Maleate 5
Ivermectin 5
Probiotic (Unknown) 5
Selamectin 4
Famotidine 4
Milbemycin Oxime + Praziquantel 4
Lotilaner 4
Estradiol + Trenbolone Acetate + Tylosin Tartrate 4

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Flatulence, bloating and distension, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (126 here).

Similar death-coded share

Nearest other reactions by death-coded share (16.7% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Flatulence, bloating and distension (#1281 of 2,481 by report volume); death-coded 16.7%. PlainBreed reaction plate · death-coded report count stamp 21 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →