Reaction profile

The FDA adverse-event record for missing cap

358 FDA adverse-event reports reference missing cap (VeDDRA 99016). See the species, breeds, and drugs most associated with it below.

358
reports citing this reaction
0.3%
death-coded share
Unknown
most-affected species
Clotrimazole, Gentamicin Sulfate, Mometasone Furoate Monohydrate
most-associated drug
Verify with FDA CVM →
358
Total Reports
1
Deaths
0.3%
Death Rate

Species Most Affected

Unknown 354
Dog 2
Cattle 1
Cat 1

Breeds Most Affected

Unknown 355
Holstein-Friesian also known as Holstein 1
Doberman Pinscher 1
Cat (unknown) 1

Associated Drugs

Clotrimazole, Gentamicin Sulfate, Mometasone Furoate Monohydrate 34
Moxidectin 21
Selamectin 16
Orbifloxacin, Mometasone, Posaconazole 16
Enrofloxacin 15
Cephapirin Benzathine 13
Selamectin;Sarolaner 13
Acepromazine Maleate 12
Doramectin 11
Protamine Zinc Recombinant Human Insulin 10
Orbiflox/Momet/Posaco Eardrops 9
Polysulfated Glycosaminoglycan 8
Ceftiofur Hydrochloride 8
Genta/Betamet/Clotrim Ear Oint 8
Ketamine Hydrochloride 7
Betamethasone Valerate, Clotrimazole, Gentamicin Sulfate 7
Genta/Momet/Clotrim Ear Oint 7
Hyaluronate Sodium 6
Orbifloxacin Oral Suspension 6
Desoxycorticosterone Pivalate 5

Missing Cap Reaction Insights

358 reports name Missing Cap; 1 recorded a death outcome (0.3% of reported events, not a population-level mortality rate). VeDDRA code: 99016.

By species: Unknown (354 reports), Dog (2 reports), Cattle (1 reports). By breed: Unknown (355), Holstein-Friesian also known as Holstein (1), Doberman Pinscher (1).

Most co-reported drugs: Clotrimazole, Gentamicin Sulfate, Mometasone Furoate Monohydrate (34 reports), Moxidectin (21 reports), Selamectin (16 reports), Orbifloxacin, Mometasone, Posaconazole (16 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.