Reaction profile

The FDA adverse-event record for nasal irritation

51 FDA adverse-event reports reference nasal irritation (VeDDRA 1637). See the species, breeds, and drugs most associated with it below.

51
reports citing this reaction
3.9%
death-coded share
Human
most-affected species
Famotidine
most-associated drug
Verify with FDA CVM →
51
Total Reports
2
Deaths
3.9%
Death Rate

Species Most Affected

Human 27
Dog 17
Cat 3
Horse 2
Donkey 2

Breeds Most Affected

Unknown 27
Crossbred Canine/dog 3
Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 3
Chihuahua 3
Domestic Shorthair 2
Bulldog 2
Havanese 2
Donkey (other) 2
Retriever - Labrador 1
Miniature 1

Associated Drugs

Famotidine 5
Imidacloprid + Moxidectin 4
Milbemycin Oxime + Spinosad 4
Tylosin Tartrate 4
Detomidine Hydrochloride 4
Furosemide 4
Cyclosporine A 3
Selamectin 3
Capromorelin Tartrate 3
Pimobendan 3
Maropitant Citrate 3
Sucralfate 3
Spinosad 2
Trazodone 2
Metformin 2
Montelukast Sodium 2
Fluralaner Chew Tablets 2
Deracoxib 2
Polysulfated Glycosaminoglycan 2
Methocarbamol 2

Nasal irritation Reaction Insights

51 reports name Nasal irritation; 2 recorded a death outcome (3.9% of reported events, not a population-level mortality rate). VeDDRA code: 1637.

By species: Human (27 reports), Dog (17 reports), Cat (3 reports). By breed: Unknown (27), Crossbred Canine/dog (3), Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) (3).

Most co-reported drugs: Famotidine (5 reports), Imidacloprid + Moxidectin (4 reports), Milbemycin Oxime + Spinosad (4 reports), Tylosin Tartrate (4 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.