Reaction profile

The FDA adverse-event record for nasal irritation

53 FDA reports name nasal irritation, a lower-volume reaction in the CVM extract (VeDDRA 1637). Plate stamps and neighbourhood peers follow.

#1711 of 2,481
by report volume (all reactions)
53
reports citing this reaction
3.8%
death-coded share
Human
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Nasal irritation has 53 reports now versus 53 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Nasal irritation changes

FDA AER · VeDDRA plate

Code 1637 VOL-LOW

VOL-LOW · DEATH-LOW · MID-PACK · PHOTO-FINISH · SPECIES-HUMAN · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 53 reports
  • DEATH-LOW 3.8%
  • MID-PACK #1711/2481
  • PHOTO-FINISH Bloody foam in mouth…
  • SPECIES-HUMAN Human · 27
  • DRUG-LEAD Famotidine · 5
  • DESK-WIDE 17 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Bloody foam in mouth and nose (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Nasal irritation

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Bloody foam in mouth… · near53Decreased skin turgor · near53Easily startled · near53Footpad disorder NOS · near53Nasal irritation · this reac…53Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Nasal irritation

Nasal irritation: low death-coded share in the FDA AER plate

Signature read: 2 death-coded reports is a thin tail count for Nasal irritation in the CVM extract. Report volume is lower-third scale: 53 named reports in the openFDA extract. Death-coded share is lower-third: 2 of 53 reports (3.8% of named reports). Nearest volume peer: Bloody foam in mouth and nose (±0 reports). Lead species Human (27). Lead co-reported drug Famotidine (5).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Famotidine appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Human 27
Dog 19
Cat 3
Horse 2
Donkey 2

Breeds Most Affected

Unknown 27
Crossbred Canine/dog 3
Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 3
Chihuahua 3
Domestic Shorthair 2
Bulldog 2
Havanese 2
Donkey (other) 2
Retriever - Labrador 1
Miniature 1

Associated Drugs

Famotidine 5
Imidacloprid + Moxidectin 4
Milbemycin Oxime + Spinosad 4
Tylosin Tartrate 4
Detomidine Hydrochloride 4
Furosemide 4
Cyclosporine A 3
Selamectin 3
Capromorelin Tartrate 3
Pimobendan 3
Maropitant Citrate 3
Sucralfate 3
Spinosad 2
Trazodone 2
Metformin 2
Montelukast Sodium 2
Fluralaner Chew Tablets 2
Deracoxib 2
Polysulfated Glycosaminoglycan 2
Methocarbamol 2

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Nasal irritation, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (53 here).

Similar death-coded share

Nearest other reactions by death-coded share (3.8% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Nasal irritation (#1711 of 2,481 by report volume); death-coded 3.8%. PlainBreed reaction plate · death-coded report count stamp 2 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →