Reaction profile

The FDA adverse-event record for anal and rectal disorder nos

181 FDA adverse-event reports reference anal and rectal disorder nos (VeDDRA 2560). See the species, breeds, and drugs most associated with it below.

181
reports citing this reaction
13.3%
death-coded share
Dog
most-affected species
Bedinvetmab
most-associated drug
Verify with FDA CVM →
181
Total Reports
24
Deaths
13.3%
Death Rate

Species Most Affected

Dog 146
Cat 31
Horse 1
Cattle 1
Pig 1
Ferret 1

Breeds Most Affected

Domestic Shorthair 24
Retriever - Labrador 19
Crossbred Canine/dog 11
Shih Tzu 10
Shepherd Dog - German 8
Dog (unknown) 8
Terrier - Boston 6
Chihuahua 6
Terrier - Bull - American Pit 4
Terrier - Yorkshire 4

Associated Drugs

Bedinvetmab 20
Oclacitinib Maleate 19
Carprofen 15
Gabapentin 14
Prednisone 13
Fluralaner Chew Tablets 11
Milbemycin Oxime + Praziquantel 11
Melarsomine Dihydrochloride 9
Milbemycin Oxime + Spinosad 9
Fluralaner 13.64% 12-Week Chew 9
Afoxolaner 8
Metronidazole 7
Maropitant Citrate 7
Frunevetmab 7
Selamectin 6
Anti-Il31 Mab Mcs Lot #1283563 6
Meloxicam 6
Lotilaner 6
Buprenorphine 5
Ivermectin + Pyrantel As Pamoate Salt 5

Anal and rectal disorder NOS Reaction Insights

181 reports name Anal and rectal disorder NOS; 24 recorded a death outcome (13.3% of reported events, not a population-level mortality rate). VeDDRA code: 2560.

By species: Dog (146 reports), Cat (31 reports), Horse (1 reports). By breed: Domestic Shorthair (24), Retriever - Labrador (19), Crossbred Canine/dog (11).

Most co-reported drugs: Bedinvetmab (20 reports), Oclacitinib Maleate (19 reports), Carprofen (15 reports), Gabapentin (14 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.