Reaction profile

The FDA adverse-event record for respiratory sound

378 FDA reports name respiratory sound, a high-volume reaction in the CVM extract (VeDDRA 1176). Plate stamps and neighbourhood peers follow.

#760 of 2,481
by report volume (all reactions)
378
reports citing this reaction
35.4%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Respiratory sound has 378 reports now versus 373 in that prior snapshot: 5 more (1.3%).

Report change
+5
Death-coded reports
+2
Death-coded share
+0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Respiratory sound changes

FDA AER · VeDDRA plate

Code 1176 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 378 reports
  • DEATH-HOT 35.4%
  • MID-PACK #760/2481
  • PHOTO-FINISH Increased drinking
  • SPECIES-DOG Dog · 241
  • DRUG-LEAD Maropitant Citrate · 30
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Increased drinking (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Respiratory sound

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Increased drinking · near378Pinnal oedema · near378Respiratory sound · this rea…378WBC, URINE · near378Abnormal test result · near377Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Respiratory sound

Respiratory sound: high death-coded share in the FDA AER plate

Signature read: 134 death-coded reports is a heavy tail count for Respiratory sound in the CVM extract. Report volume is upper-third scale: 378 named reports in the openFDA extract. Death-coded share is upper-third: 134 of 378 reports (35.4% of named reports). Nearest volume peer: Increased drinking (±0 reports). Lead species Dog (241). Lead co-reported drug Maropitant Citrate (30).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 241
Cat 119
Horse 9
Cattle 7
Goat 2

Breeds Most Affected

Domestic Shorthair 52
Crossbred Canine/dog 35
Domestic (unspecified) 34
Retriever - Labrador 17
Terrier - Yorkshire 12
Dachshund (unspecified) 9
Domestic Mediumhair 9
Beagle 8
Bulldog 8
Chihuahua 8

Associated Drugs

Maropitant Citrate 30
Carprofen 24
Cefovecin Sodium 21
Milbemycin Oxime + Spinosad 19
Furosemide 18
Enrofloxacin 18
Moxidectin 16
Cefovecin 16
Dexmedetomidine Hydrochloride 15
Selamectin 14
Spinosad 14
Nitenpyram 14
Doxycycline 14
Pimobendan 13
Prednisone 13
Buprenorphine 13
Propofol 12
Oclacitinib Maleate 12
Melarsomine Dihydrochloride 11
Meloxicam 11

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Respiratory sound, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (378 here).

Similar death-coded share

Nearest other reactions by death-coded share (35.4% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Respiratory sound (#760 of 2,481 by report volume); death-coded 35.4%. PlainBreed reaction plate · death-coded report count stamp 134 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →