Reaction profile

The FDA adverse-event record for respiratory sound

370 FDA adverse-event reports reference respiratory sound (VeDDRA 1176). See the species, breeds, and drugs most associated with it below.

370
reports citing this reaction
35.4%
death-coded share
Dog
most-affected species
Maropitant Citrate
most-associated drug
Verify with FDA CVM →
370
Total Reports
131
Deaths
35.4%
Death Rate

Species Most Affected

Dog 236
Cat 116
Horse 9
Cattle 7
Goat 2

Breeds Most Affected

Domestic Shorthair 49
Crossbred Canine/dog 35
Domestic (unspecified) 34
Retriever - Labrador 17
Terrier - Yorkshire 12
Dachshund (unspecified) 9
Domestic Mediumhair 9
Beagle 8
Bulldog 8
Maltese 8

Associated Drugs

Maropitant Citrate 28
Carprofen 23
Cefovecin Sodium 21
Milbemycin Oxime + Spinosad 19
Furosemide 18
Moxidectin 16
Cefovecin 16
Enrofloxacin 15
Selamectin 14
Dexmedetomidine Hydrochloride 14
Spinosad 14
Doxycycline 14
Pimobendan 13
Nitenpyram 13
Prednisone 13
Propofol 12
Buprenorphine 12
Oclacitinib Maleate 12
Melarsomine Dihydrochloride 11
Meloxicam 11

Respiratory sound Reaction Insights

370 reports name Respiratory sound; 131 recorded a death outcome (35.4% of reported events, not a population-level mortality rate). VeDDRA code: 1176.

By species: Dog (236 reports), Cat (116 reports), Horse (9 reports). By breed: Domestic Shorthair (49), Crossbred Canine/dog (35), Domestic (unspecified) (34).

Most co-reported drugs: Maropitant Citrate (28 reports), Carprofen (23 reports), Cefovecin Sodium (21 reports), Milbemycin Oxime + Spinosad (19 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.