Reaction profile

The FDA adverse-event record for ear canal disorder

167 FDA adverse-event reports reference ear canal disorder (VeDDRA 2567). See the species, breeds, and drugs most associated with it below.

167
reports citing this reaction
7.2%
death-coded share
Dog
most-affected species
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride
most-associated drug
Verify with FDA CVM →
167
Total Reports
12
Deaths
7.2%
Death Rate

Species Most Affected

Dog 132
Cat 34
Cattle 1

Breeds Most Affected

Domestic Shorthair 21
Retriever - Labrador 12
Retriever - Golden 9
Crossbred Canine/dog 8
Terrier (unspecified) 7
Terrier - Yorkshire 7
Dog (unknown) 6
Chihuahua 6
Shepherd Dog - German 5
Siamese 3

Associated Drugs

Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 41
Betamethasone + Florfenicol + Terbinafine 12
Gabapentin 12
Genta/Momet/Clotrim Ear Oint 11
Oclacitinib Maleate 10
Maropitant Citrate 10
Miconazole + Polymyxin B + Prednisolone 10
Orbiflox/Momet/Posaco Eardrops 10
Prednisone 9
Lidocaine 7
Florfenicol, Terbinafine Hcl, Mometasone Furoate 7
Ear Cleaner 6
Cefovecin 5
Midazolam 5
Propofol 5
Ear Cleaner (Unknown) 5
Rabies Vaccine 5
Florfenicol, Terbinafine, Betamethasone Acetate 5
Carprofen 5
Lotilaner 5

Ear canal disorder Reaction Insights

167 reports name Ear canal disorder; 12 recorded a death outcome (7.2% of reported events, not a population-level mortality rate). VeDDRA code: 2567.

By species: Dog (132 reports), Cat (34 reports), Cattle (1 reports). By breed: Domestic Shorthair (21), Retriever - Labrador (12), Retriever - Golden (9).

Most co-reported drugs: Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride (41 reports), Betamethasone + Florfenicol + Terbinafine (12 reports), Gabapentin (12 reports), Genta/Momet/Clotrim Ear Oint (11 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.