Reaction profile

The FDA adverse-event record for chewing - oral cavity disorder (see also 'pruritus')

211 FDA adverse-event reports reference chewing - oral cavity disorder (see also 'pruritus') (VeDDRA 1073). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1003 of 2,481
by report volume (all reactions)
211
reports citing this reaction
4.3%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Chewing - oral cavity disorder (see also 'Pruritus') has 211 reports now versus 211 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Chewing - oral cavity disorder (see also 'Pruritus') changes

FDA AER · VeDDRA plate

Code 1073 VOL-LOW

VOL-LOW · DEATH-LOW · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 211 reports
  • DEATH-LOW 4.3%
  • MID-PACK #1003/2481
  • PHOTO-FINISH Hyperadrenocorticism
  • SPECIES-DOG Dog · 192
  • DRUG-LEAD Milbemycin Oxime… · 67
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Hyperadrenocorticism (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Chewing - oral cavity disorder

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Chewing - oral cavity… · thi…211Hyperadrenocorticism · near211Opisthotonus · near211Self mutilation · near211Skin haemorrhage NOS · near211Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Chewing - oral cavity disorder (see also 'Pruritus')

Chewing - oral cavity disorder (see also 'Pruritus'): low death-coded share in the FDA AER plate

Signature read: Chewing - oral cavity disorder (see also 'Pruritus')'s 4.3% death-coded share is among the lowest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is lower-third: 9 of 211 reports (4.3% of named reports). Nearest volume peer: Hyperadrenocorticism (±0 reports). Lead species Dog (192). Lead co-reported drug Milbemycin Oxime + Spinosad (67).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Milbemycin Oxime + Spinosad appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 192
Cat 11
Horse 7
Other Bovine 1

Breeds Most Affected

Shepherd Dog - German 16
Retriever - Labrador 12
Chihuahua 12
Crossbred Canine/dog 11
Collie - Border 8
Retriever - Golden 8
Spaniel - Cocker American 7
Terrier (unspecified) 6
Domestic Shorthair 6
Maltese 6

Associated Drugs

Milbemycin Oxime + Spinosad 67
Spinosad 39
Afoxolaner 14
Fluralaner Chew Tablets 12
Ivermectin 8
Ivermectin + Pyrantel As Pamoate Salt 8
Milbemycin Oxime + Praziquantel 8
Oclacitinib Maleate 7
Sarolaner 7
Fipronil 10%/S Methoprene 9% Spot On 5
Cephalexin 5
Distemper Vaccine 4
Rabies Vaccine 4
Selamectin 4
Afoxolaner 2.27% Chewable Tablet (136 Mg) 4
Bordetella Vaccine 3
Ivermectin/Pyrantel Pamoate Chewable 272Mcg/652Mg 3
Ivermectin/Pyrantel Pamoate Chewable 68Mcg/163Mg 3
Levothyroxine Sodium 3
Carprofen 3

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Chewing - oral cavity disorder (see also 'Pruritus'), both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (211 here).

Similar death-coded share

Nearest other reactions by death-coded share (4.3% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Chewing - oral cavity disorder (see also 'Pruritus') (#1003 of 2,481 by report volume); death-coded 4.3%. PlainBreed reaction plate · death-coded share stamp 4.3% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →