Reaction profile

The FDA adverse-event record for painful urination

58 FDA reports name painful urination, a lower-volume reaction in the CVM extract (VeDDRA 2099). Plate stamps and neighbourhood peers follow.

#1669 of 2,481
by report volume (all reactions)
58
reports citing this reaction
20.7%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Painful urination has 58 reports now versus 58 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Painful urination changes

FDA AER · VeDDRA plate

Code 2099 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 58 reports
  • DEATH-HOT 20.7%
  • MID-PACK #1669/2481
  • PHOTO-FINISH Heart block 2nd degree
  • SPECIES-DOG Dog · 43
  • DRUG-LEAD Bedinvetmab · 12
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Heart block 2nd degree (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Painful urination

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Heart block 2nd degree · near58Muscle degeneration · near58Ocular burn · near58Painful urination · this rea…58PR-BONE MARROW, LESIO… · near58Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Painful urination

What the FDA AER plate says about Painful urination

Signature read: 58 reports place Painful urination in the lower third of FDA AER volume (#1669 of 2,481). Report volume is lower-third scale: 58 named reports in the openFDA extract. 12 of 58 reports were death-coded (20.7% of named reports, not a population mortality rate). Nearest volume peer: Heart block 2nd degree (±0 reports). Lead species Dog (43). Lead co-reported drug Bedinvetmab (12).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Bedinvetmab appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 43
Cat 13
Goat 1
Ferret 1

Breeds Most Affected

Domestic Shorthair 8
Retriever - Labrador 5
Crossbred Canine/dog 3
Beagle 3
Griffon - Brussels 2
Dog (unknown) 2
Pit Bull 2
Terrier - Rat 2
Pug 2
Terrier - Jack Russell 1

Associated Drugs

Bedinvetmab 12
Oclacitinib Maleate 6
Buprenorphine 5
Robenacoxib 3
Milbemycin Oxime + Praziquantel 3
Carprofen 3
Milbemycin Oxime + Spinosad 2
Trilostane 2
Estriol Tablets 2
Enrofloxacin 2
Prescription Urinary Diet 2
Afoxolaner 2
Meloxicam 2
Gabapentin 2
Midazolam 2
Propofol 2
Isoflurane 2
Cefazolin 2
Cefovecin Sodium 2
Proin 2

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Painful urination, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (58 here).

Similar death-coded share

Nearest other reactions by death-coded share (20.7% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Painful urination (#1669 of 2,481 by report volume); death-coded 20.7%. PlainBreed reaction plate · report volume stamp 58 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →