Reaction profile

The FDA adverse-event record for pinnal necrosis

37 FDA reports name pinnal necrosis, a lower-volume reaction in the CVM extract (VeDDRA 362). Plate stamps and neighbourhood peers follow.

#1901 of 2,481
by report volume (all reactions)
37
reports citing this reaction
10.8%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Pinnal necrosis has 37 reports now versus 36 in that prior snapshot: 1 more (2.8%).

Report change
+1
Death-coded reports
+0
Death-coded share
−0.3 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Pinnal necrosis changes

FDA AER · VeDDRA plate

Code 362 VOL-TRACE

VOL-TRACE · DEATH-ELEV · LOWER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 37 reports
  • DEATH-ELEV 10.8%
  • LOWER-Q #1901/2481
  • PHOTO-FINISH Blistering of mouth
  • SPECIES-DOG Dog · 25
  • DRUG-LEAD Carprofen · 8
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Blistering of mouth (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Pinnal necrosis

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Blistering of mouth · near37CARBON DIOXIDE HIGH,… · near37Cartilage degeneration · near37Cleft palate · near37Pinnal necrosis · this react…37Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Pinnal necrosis

What the FDA AER plate says about Pinnal necrosis

Signature read: 37 reports place Pinnal necrosis in the lower third of FDA AER volume (#1901 of 2,481). Report volume is lower-third scale: 37 named reports in the openFDA extract. 4 of 37 reports were death-coded (10.8% of named reports, not a population mortality rate). Nearest volume peer: Blistering of mouth (±0 reports). Lead species Dog (25). Lead co-reported drug Carprofen (8).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Carprofen appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 25
Cat 10
Rabbit 1
Cattle 1

Breeds Most Affected

Domestic Shorthair 6
Shih Tzu 5
Chihuahua 3
Cat (other) 3
Boxer (German Boxer) 2
Schnauzer - Miniature 2
Siberian Husky 1
Terrier - Toy Fox 1
Dachshund (unspecified) 1
Poodle - Toy 1

Associated Drugs

Carprofen 8
Cefovecin 3
Meloxicam 3
Polymyxin B Sulfate;Oxytetracycline Hcl 3
Selamectin;Sarolaner 3
Epsiprantel 3
Feline Calicivirus, Strain F-9, Passage 7, Lot A;Feline Viral Rhinotracheitis, S 3
Rabies Virus, 3
Thiabendazole, Dexamethasone, Neomycin Sulfate 3
Tobramycin 2
Dexmedetomidine Hydrochloride 2
Leptospira Canicola L-15 Strain C-51; Leptospira Grippotyphosa 1550 Lot 10005 St 2
Propofol 2
Hydromorphone Hcl 2
Moxidectin 2
Prednisone 2
Florfenicol/Terbinafine Hydrochloride/Mometasone Furoate 2
Alfaxalone 2
Spinosad 1
Pyrantel Pamoate 1

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Pinnal necrosis (#1901 of 2,481 by report volume); death-coded 10.8%. PlainBreed reaction plate · report volume stamp 37 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →