Reaction profile

The FDA adverse-event record for pinnal necrosis

36 FDA adverse-event reports reference pinnal necrosis (VeDDRA 362). See the species, breeds, and drugs most associated with it below.

36
reports citing this reaction
11.1%
death-coded share
Dog
most-affected species
Carprofen
most-associated drug
Verify with FDA CVM →
36
Total Reports
4
Deaths
11.1%
Death Rate

Species Most Affected

Dog 24
Cat 10
Rabbit 1
Cattle 1

Breeds Most Affected

Domestic Shorthair 6
Shih Tzu 5
Chihuahua 3
Cat (other) 3
Boxer (German Boxer) 2
Schnauzer - Miniature 2
Siberian Husky 1
Terrier - Toy Fox 1
Dachshund (unspecified) 1
Poodle - Toy 1

Associated Drugs

Carprofen 6
Cefovecin 3
Meloxicam 3
Polymyxin B Sulfate;Oxytetracycline Hcl 3
Selamectin;Sarolaner 3
Epsiprantel 3
Feline Calicivirus, Strain F-9, Passage 7, Lot A;Feline Viral Rhinotracheitis, S 3
Rabies Virus, 3
Thiabendazole, Dexamethasone, Neomycin Sulfate 3
Tobramycin 2
Dexmedetomidine Hydrochloride 2
Leptospira Canicola L-15 Strain C-51; Leptospira Grippotyphosa 1550 Lot 10005 St 2
Propofol 2
Hydromorphone Hcl 2
Moxidectin 2
Prednisone 2
Florfenicol/Terbinafine Hydrochloride/Mometasone Furoate 2
Spinosad 1
Pyrantel Pamoate 1
Glycosaminoglycan Polysulfate 1

Pinnal necrosis Reaction Insights

36 reports name Pinnal necrosis; 4 recorded a death outcome (11.1% of reported events, not a population-level mortality rate). VeDDRA code: 362.

By species: Dog (24 reports), Cat (10 reports), Rabbit (1 reports). By breed: Domestic Shorthair (6), Shih Tzu (5), Chihuahua (3).

Most co-reported drugs: Carprofen (6 reports), Cefovecin (3 reports), Meloxicam (3 reports), Polymyxin B Sulfate;Oxytetracycline Hcl (3 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.