Reaction profile

The FDA adverse-event record for implant site reaction nos

Name: Implant site reaction NOS - FDA Animal Adverse Reaction
Creator: PlainBreed
License: https://open.fda.gov/license/

16 FDA reports name implant site reaction nos, a lower-volume reaction in the CVM extract (VeDDRA 64). Plate stamps and neighbourhood peers follow.

#2276 of 2,481
by report volume (all reactions): 16
reports citing this reaction: 0.0%
death-coded share: Ferret
most-affected species

Compiled by PlainBreed

Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Implant site reaction NOS has 16 reports now versus 16 in that prior snapshot: 0 the same number of (0.0%).

Report change: +0
Death-coded reports: +0
Death-coded share: +0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

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FDA AER · VeDDRA plate

Code 64 VOL-TRACE

VOL-TRACE · DEATH-RARE · BOTTOM-DECILE · PHOTO-FINISH · SPECIES-FERRET · DRUG-LEAD · DESK-MID · BOOK-FULL

VOL-TRACE 16 reports
DEATH-RARE 0.0%
BOTTOM-DECILE #2276/2481
PHOTO-FINISH Abdominal transudate
SPECIES-FERRET Ferret · 10
DRUG-LEAD Deslorelin · 8
DESK-MID 7 breeds
BOOK-FULL 8/8 fields

Nearest volume peer: Abdominal transudate (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Implant site reaction NOS

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

FDA AER report volume · neighbourhood around Implant site reaction NOS

Implant site reaction NOS: low death-coded share in the FDA AER plate

Signature read: Implant site reaction NOS's 0.0% death-coded share is among the lowest in the openFDA reaction corpus. Report volume is lower-third scale: 16 named reports in the openFDA extract. Death-coded share is lower-third: 0 of 16 reports (0.0% of named reports). Nearest volume peer: Abdominal transudate (±0 reports). Lead species Ferret (10). Lead co-reported drug Deslorelin (8).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Deslorelin appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Ferret 10

Dog 3

Cattle 2

Cat 1

Breeds Most Affected

Domestic ferret (Pet ferret) 8

Mixed (Cattle) 2

Unknown 2

Domestic Shorthair 1

Retriever - Labrador 1

Terrier - Yorkshire 1

Dog (unknown) 1

Associated Drugs

Deslorelin 8

Suture 2

Progesterone;Estradiol Benzoate 2

Deslorelin Acetate 2

Robenacoxib 1

Ketamine 1

Midazolam 1

Isoflurane 1

Ampicillin Trihydrate 1

Betamethasone + Florfenicol + Terbinafine 1

Milbemycin Oxime + Spinosad 1

Hydrocodone 1

Device: Suture 1

What to do with this reaction

Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
Browse the full reaction directory to compare report counts across reaction types. All reactions

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Implant site reaction NOS (#2276 of 2,481 by report volume); death-coded 0.0%. PlainBreed reaction plate · death-coded share stamp 0.0% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →