Reaction profile

The FDA adverse-event record for urobilinogen high, urine

18 FDA adverse-event reports reference urobilinogen high, urine (VeDDRA 99366). See the species, breeds, and drugs most associated with it below.

18
reports citing this reaction
33.3%
death-coded share
Dog
most-affected species
Deracoxib
most-associated drug
Verify with FDA CVM →
18
Total Reports
6
Deaths
33.3%
Death Rate

Species Most Affected

Dog 18

Breeds Most Affected

Crossbred Canine/dog 4
Shepherd Dog - German 2
Shiba Inu 1
Boxer (German Boxer) 1
Mountain Dog - Bernese 1
Ridgeback - Rhodesian 1
Greyhound 1
Beagle 1
Siberian Husky 1
Great Pyrenees 1

Associated Drugs

Deracoxib 6
Carprofen 5
Ivermectin, Pyrantel 1
Cefovecin Sodium 1
Milbemycin Oxime + Spinosad 1
Imidacloprid + Moxidectin 1
Diphenhydramine 1
Ivermectin 272Mcg, Pyrantel 227Mg 1
Ivermectin/Pyrantel Pamoate Chewable 272Mcg/652Mg 1
Fluralaner Chew Tablets 1
Polysulfated Glycosaminoglycan 1
Ibuprofen 1
Tramadol 1
Moxidectin 1
Glucosamine/Chondroitin With Avocado/Soybean Unsaponifiables 1
Butorphanol Tartrate 1
Dexmedetomidine 1
Atipameole Hcl 1
Famotidine 1
Firocoxib 1

UROBILINOGEN HIGH, URINE Reaction Insights

18 reports name UROBILINOGEN HIGH, URINE; 6 recorded a death outcome (33.3% of reported events, not a population-level mortality rate). VeDDRA code: 99366.

By species: Dog (18 reports). By breed: Crossbred Canine/dog (4), Shepherd Dog - German (2), Shiba Inu (1).

Most co-reported drugs: Deracoxib (6 reports), Carprofen (5 reports), Ivermectin, Pyrantel (1 reports), Cefovecin Sodium (1 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.