Reaction profile

The FDA adverse-event record for dull

652 FDA reports name dull, a high-volume reaction in the CVM extract (VeDDRA 2274). Plate stamps and neighbourhood peers follow.

#538 of 2,481
by report volume (all reactions)
652
reports citing this reaction
28.7%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Dull has 652 reports now versus 624 in that prior snapshot: 28 more (4.5%).

Report change
+28
Death-coded reports
+9
Death-coded share
+0.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Dull changes

FDA AER · VeDDRA plate

Code 2274 VOL-MID

VOL-MID · DEATH-HOT · UPPER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 652 reports
  • DEATH-HOT 28.7%
  • UPPER-Q #538/2481
  • PHOTO-FINISH Low thyroxine (T4)
  • SPECIES-DOG Dog · 449
  • DRUG-LEAD Maropitant Citrate · 93
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Low thyroxine (T4) (±1 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Dull

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Low thyroxine (T4) · near653Dull · this reaction652Tongue disorder NOS · near649Liver failure · near648Patient instructions… · near647Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Dull

Dull: high death-coded share in the FDA AER plate

Signature read: 187 death-coded reports is a heavy tail count for Dull in the CVM extract. Report volume is upper-third scale: 652 named reports in the openFDA extract. Death-coded share is upper-third: 187 of 652 reports (28.7% of named reports). Nearest volume peer: Low thyroxine (T4) (±1 reports). Lead species Dog (449). Lead co-reported drug Maropitant Citrate (93).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 449
Cat 152
Horse 39
Cattle 10
Fox 1
Goat 1

Breeds Most Affected

Domestic Shorthair 97
Retriever - Labrador 41
Crossbred Canine/dog 38
Chihuahua 21
Shih Tzu 17
Quarter Horse 17
Retriever - Golden 16
Terrier - Yorkshire 14
Spitz - German Pomeranian 12
Maltese 12

Associated Drugs

Maropitant Citrate 93
Buprenorphine 59
Moxidectin 40
Carprofen 39
Milbemycin Oxime + Spinosad 38
Trilostane 38
Bedinvetmab 35
Gabapentin 33
Fluid Therapy 29
Milbemycin Oxime + Praziquantel 24
Ondansetron 24
Afoxolaner 23
Pyrantel Pamoate;Sarolaner 22
Fluralaner Chew Tablets 20
Propofol 20
Prednisone 20
Midazolam 20
Oclacitinib Maleate 20
Diphenhydramine 19
Isoflurane 18

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Dull, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (28.7% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Dull (#538 of 2,481 by report volume); death-coded 28.7%. PlainBreed reaction plate · death-coded report count stamp 187 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →