Reaction profile

The FDA adverse-event record for accidental exposure

12,968 FDA reports name accidental exposure, a high-volume reaction in the CVM extract (VeDDRA 99809). Plate stamps and neighbourhood peers follow.

#34 of 2,481
by report volume (all reactions)
12,968
reports citing this reaction
2.6%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Accidental exposure has 12,968 reports now versus 12,773 in that prior snapshot: 195 more (1.5%).

Report change
+195
Death-coded reports
+8
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Accidental exposure changes

FDA AER · VeDDRA plate

Code 99809 VOL-HIGH

VOL-HIGH · DEATH-LOW · TOP-DECILE · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-HIGH 12,968 reports
  • DEATH-LOW 2.6%
  • TOP-DECILE #34/2481
  • PHOTO-FINISH Shaking
  • SPECIES-DOG Dog · 6,975
  • DRUG-LEAD Milbemycin Oxime… · 2,067
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Shaking (±19 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Accidental exposure

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Depression · near13060INEFFECTIVE, HOOKS · near13039Containers, Damaged · near13017Accidental exposure · this r…12968Shaking · near12949Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Accidental exposure

Accidental exposure: low death-coded share in the FDA AER plate

Signature read: 12,968 reports place Accidental exposure in the upper third of FDA AER volume (#34 of 2,481). Report volume is upper-third scale: 12,968 named reports in the openFDA extract. Death-coded share is lower-third: 341 of 12,968 reports (2.6% of named reports). Nearest volume peer: Shaking (±19 reports). Lead species Dog (6,975). Lead co-reported drug Milbemycin Oxime + Spinosad (2,067).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Milbemycin Oxime + Spinosad appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 6,975
Human 3,755
Cat 1,846
Unknown 132
Horse 96
Cattle 66
Chicken 26
Pig 21
Turkey 12
Sheep 8

Breeds Most Affected

Unknown 3,934
Domestic Shorthair 938
Crossbred Canine/dog 688
Retriever - Labrador 633
Chihuahua 479
Dog (unknown) 445
Terrier - Yorkshire 408
Domestic (unspecified) 262
Cat (unknown) 239
Dachshund (unspecified) 227

Associated Drugs

Milbemycin Oxime + Spinosad 2,067
Spinosad 1,291
Carprofen 601
Selamectin 567
Imidacloprid + Moxidectin 520
Oclacitinib Maleate 379
Ivermectin 330
Sarolaner 305
Fluralaner Spot-On Solution 303
Phenylpropanolamine Hcl 215
Cephalexin 207
Ivermectin + Pyrantel As Pamoate Salt 202
Emodepside + Praziquantel 200
Eprinomectin + Esafoxolaner + Praziquantel 191
Tilmicosin Phosphate 190
Meloxicam 172
Nitenpyram 172
Afoxolaner 171
Moxidectin 165
Maropitant Citrate 152

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Accidental exposure, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (12,968 here).

Similar death-coded share

Nearest other reactions by death-coded share (2.6% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Accidental exposure (#34 of 2,481 by report volume); death-coded 2.6%. PlainBreed reaction plate · report volume stamp 12,968 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →