Panniculitis

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VeDDRA Code: 951

110 adverse event reports referencing this reaction

110
Total Reports
19
Deaths
1730.0%
Death Rate

Species Most Affected

Dog 93
Cat 16
Cattle 1

Breeds Most Affected

Domestic Shorthair 9
Chihuahua 9
Retriever - Labrador 8
Maltese 6
Shepherd Dog - Australian 6
Terrier (unspecified) 5
Terrier - Yorkshire 3
Domestic Mediumhair 3
Bichon Frise 3
Retriever - Golden 3

Associated Drugs

Carprofen 18
Oclacitinib Maleate 15
Moxidectin 13
Cefovecin 13
Prednisone 12
Maropitant Citrate 11
Rabies Virus, Kv 8
Enrofloxacin 7
Tramadol 7
Methylprednisolone Acetate 7
Afoxolaner 7
Gabapentin 7
Meloxicam 6
Isoflurane 5
Cyclosporine 5
Doxycycline 5
Ivermectin + Pyrantel As Pamoate Salt 5
Bedinvetmab 5
Buprenorphine 4
Famotidine 4

Data Summary

Metric Value
Total reports referencing reaction 110
Reports with fatal outcome 19
Case-fatality rate (reported events) 1730.0%
Species observed 3
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 951.

Panniculitis Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 110 adverse event reports that reference Panniculitis as a reaction term, including 19 reports with a death outcome — a 1730.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 951, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Panniculitis appears most frequently in reports for Dog (93 reports), Cat (16 reports), Cattle (1 reports) — with Dog dominating at 93 entries. Within those species, the breeds most often named alongside this reaction are Domestic Shorthair (9), Chihuahua (9), Retriever - Labrador (8). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Panniculitis are Carprofen (18 reports), Oclacitinib Maleate (15 reports), Moxidectin (13 reports), Cefovecin (13 reports), with Carprofen appearing alongside this reaction in 18 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial