Reaction profile

The FDA adverse-event record for biting - pruritus (see also 'behavioural disorders')

591 FDA reports name biting - pruritus (see also 'behavioural disorders'), a high-volume reaction in the CVM extract (VeDDRA 2608). Plate stamps and neighbourhood peers follow.

#580 of 2,481
by report volume (all reactions)
591
reports citing this reaction
1.7%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Biting - pruritus (see also 'Behavioural disorders') has 341 reports now versus 341 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Biting - pruritus (see also 'Behavioural disorders') changes

FDA AER · VeDDRA plate

Code 2608 VOL-MID

VOL-MID · DEATH-LOW · UPPER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 591 reports
  • DEATH-LOW 1.7%
  • UPPER-Q #580/2481
  • PHOTO-FINISH Tooth disorder
  • SPECIES-DOG Dog · 188
  • DRUG-LEAD Nitenpyram · 68
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Tooth disorder (±1 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Biting - pruritus

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Enlarged lymph node (… · near594INEFFECTIVE, ANTIBIOT… · near594Tooth disorder · near592Biting - pruritus (se… · thi…591Not urinating · near587Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Biting - pruritus (see also 'Behavioural disorders')

Biting - pruritus (see also 'Behavioural disorders'): low death-coded share in the FDA AER plate

Signature read: Biting - pruritus (see also 'Behavioural disorders')'s 1.7% death-coded share is among the lowest in the openFDA reaction corpus. Report volume is upper-third scale: 591 named reports in the openFDA extract. Death-coded share is lower-third: 10 of 591 reports (1.7% of named reports). Nearest volume peer: Tooth disorder (±1 reports). Lead species Dog (188). Lead co-reported drug Nitenpyram (68).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Nitenpyram appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 188
Cat 150
Horse 2
Donkey 1

Breeds Most Affected

Domestic Shorthair 88
Domestic Longhair 20
Crossbred Canine/dog 16
Retriever - Labrador 12
Domestic Mediumhair 12
Shepherd Dog - German 10
Chihuahua 9
Pit Bull 8
Terrier - Yorkshire 8
Shih Tzu 8

Associated Drugs

Nitenpyram 68
Afoxolaner 34
Fluralaner Spot-On Solution 32
Milbemycin Oxime + Spinosad 21
Fluralaner Chew Tablets 20
Selamectin;Sarolaner 19
Fluralaner 13.64% 12-Week Chew 19
Pyrantel Pamoate;Sarolaner 19
Lotilaner 18
Imidacloprid + Moxidectin 14
Sarolaner 13
Selamectin 12
Milbemycin Oxime + Praziquantel 9
Ivermectin + Pyrantel As Pamoate Salt 8
Fluralaner/Moxidectin Spot-On 8
Flea Collar 4
Cefovecin 3
Ivermectin 3
Flumethrin-Imidacloprid 3
Gabapentin 3

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Biting - pruritus (see also 'Behavioural disorders'), both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (591 here).

Similar death-coded share

Nearest other reactions by death-coded share (1.7% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Biting - pruritus (see also 'Behavioural disorders') (#580 of 2,481 by report volume); death-coded 1.7%. PlainBreed reaction plate · death-coded share stamp 1.7% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →