Dispenser, Abnormal

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VeDDRA Code: 99010

2,345 adverse event reports referencing this reaction

2,345
Total Reports
2
Deaths
10.0%
Death Rate

Species Most Affected

Unknown 2,153
Human 158
Cat 14
Dog 12
Cattle 6
Horse 2

Breeds Most Affected

Unknown 2,312
Domestic Shorthair 7
Cattle (unknown) 4
Cat (unknown) 3
Domestic (unspecified) 1
Jersey 1
Poodle - Miniature 1
Chow Chow 1
Rottweiler 1
Pointing Dog - German Short-haired 1

Associated Drugs

Meloxicam 469
Hydrocortisone Aceponate/Miconazole Nitrate/Gentamicin Sulfate 368
Fluralaner Spot-On Solution 323
Gentamicin Sulfate + Hydrocortisone Aceponate + Miconazole Nitrate 203
Cyclosporine 168
Cyclosporine A 93
Ciclesonide 89
Equipment 83
Metronidazole 62
Gentamicin Sulfate, Hydrocortisone Aceponate, Miconazole Nitrate 54
Vetpen Starter Kit 54
Enrofloxacin + Silver Sulfadiazine 22
Zeranol 21
Betamethasone Valerate + Gentamicin Sulfate 17
Triamcinolone Acetonide 16
Omeprazole 14
Ponazuril 14
Hyaluronic Acid 13
Orbifloxacin Oral Suspension 13
Tresaderm Dermatological Solution 13

Data Summary

Metric Value
Total reports referencing reaction 2,345
Reports with fatal outcome 2
Case-fatality rate (reported events) 10.0%
Species observed 6
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 99010.

Dispenser, Abnormal Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 2,345 adverse event reports that reference Dispenser, Abnormal as a reaction term, including 2 reports with a death outcome — a 10.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 99010, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Dispenser, Abnormal appears most frequently in reports for Unknown (2,153 reports), Human (158 reports), Cat (14 reports) — with Unknown dominating at 2,153 entries. Within those species, the breeds most often named alongside this reaction are Unknown (2,312), Domestic Shorthair (7), Cattle (unknown) (4). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Dispenser, Abnormal are Meloxicam (469 reports), Hydrocortisone Aceponate/Miconazole Nitrate/Gentamicin Sulfate (368 reports), Fluralaner Spot-On Solution (323 reports), Gentamicin Sulfate + Hydrocortisone Aceponate + Miconazole Nitrate (203 reports), with Meloxicam appearing alongside this reaction in 469 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial