Reaction profile

The FDA adverse-event record for intussusception

61 FDA adverse-event reports reference intussusception (VeDDRA 329). See the species, breeds, and drugs most associated with it below.

61
reports citing this reaction
44.3%
death-coded share
Dog
most-affected species
Maropitant Citrate
most-associated drug
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61
Total Reports
27
Deaths
44.3%
Death Rate

Species Most Affected

Dog 46
Cat 9
Chicken 3
Horse 2
Cattle 1

Breeds Most Affected

Crossbred Canine/dog 7
Shepherd Dog - German 7
Retriever - Labrador 5
Dog (unknown) 4
Domestic Shorthair 4
Terrier - Yorkshire 3
Bloodhound 2
Chicken (unknown) 2
Doberman Pinscher 2
Domestic Mediumhair 2

Associated Drugs

Maropitant Citrate 16
Metronidazole 6
Ivermectin + Pyrantel As Pamoate Salt 5
Milbemycin Oxime + Praziquantel 4
Maropitant 3
Meloxicam 3
Milbemycin Oxime + Spinosad 3
Sucralfate 3
Cefovecin 3
Afoxolaner 3
Carprofen 3
Rabies Virus, Kv 3
Moxidectin 3
Cefovecin Sodium 2
Ivermectin 2
Anesthetic 2
Fenbendazole 2
Tylosin Tartrate 2
Narasin + Nicarbazin 2
Amoxicillin 2

Intussusception Reaction Insights

61 reports name Intussusception; 27 recorded a death outcome (44.3% of reported events, not a population-level mortality rate). VeDDRA code: 329.

By species: Dog (46 reports), Cat (9 reports), Chicken (3 reports). By breed: Crossbred Canine/dog (7), Shepherd Dog - German (7), Retriever - Labrador (5).

Most co-reported drugs: Maropitant Citrate (16 reports), Metronidazole (6 reports), Ivermectin + Pyrantel As Pamoate Salt (5 reports), Milbemycin Oxime + Praziquantel (4 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.