Chemical burn

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VeDDRA Code: 928

91 adverse event reports referencing this reaction

91
Total Reports
5
Deaths
550.0%
Death Rate

Species Most Affected

Cat 56
Dog 17
Horse 11
Human 5
Camel 1
Cattle 1

Breeds Most Affected

Domestic Shorthair 29
Cat (other) 9
Domestic Longhair 7
Unknown 6
Quarter Horse 5
Domestic Mediumhair 4
Mixed (Dog) 3
Horse (unknown) 2
Shepherd Dog - Australian 2
Maine Coon 2

Associated Drugs

Selamectin;Sarolaner 20
Selamectin 19
Fluralaner Spot-On Solution 10
Ivermectin(1.55%)/Praziquantel(7.75%) Paste 5
Fipronil 10%/S Methoprene 9% Spot On 4
Imidacloprid + Moxidectin 4
Maropitant Citrate 4
Ivermectin + Praziquantel 4
Ivermectin + Pyrantel As Pamoate Salt 2
Ivermectin 2
Chlorhexidine Gluconate + Phytosphingosine Salicyloyl 2
Hydrogen Peroxide 2
Robenacoxib 2
Fluralaner/Moxidectin Spot-On 2
Nitenpyram 2
Buprenorphine 2
Eprinomectin + Esafoxolaner + Praziquantel 2
Spinosad 1
Ivermectin/Pyrantel Pamoate Chewable 136Mcg/326Mg 1
Toceranib Phosphate 1

Data Summary

Metric Value
Total reports referencing reaction 91
Reports with fatal outcome 5
Case-fatality rate (reported events) 550.0%
Species observed 6
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 928.

Chemical burn Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 91 adverse event reports that reference Chemical burn as a reaction term, including 5 reports with a death outcome — a 550.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 928, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Chemical burn appears most frequently in reports for Cat (56 reports), Dog (17 reports), Horse (11 reports) — with Cat dominating at 56 entries. Within those species, the breeds most often named alongside this reaction are Domestic Shorthair (29), Cat (other) (9), Domestic Longhair (7). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Chemical burn are Selamectin;Sarolaner (20 reports), Selamectin (19 reports), Fluralaner Spot-On Solution (10 reports), Ivermectin(1.55%)/Praziquantel(7.75%) Paste (5 reports), with Selamectin;Sarolaner appearing alongside this reaction in 20 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial