Reaction profile

The FDA adverse-event record for pituitary disorder nos

Name: Pituitary disorder NOS - FDA Animal Adverse Reaction
Creator: PlainBreed
License: https://open.fda.gov/license/

39 FDA reports name pituitary disorder nos, a lower-volume reaction in the CVM extract (VeDDRA 402). Plate stamps and neighbourhood peers follow.

#1865 of 2,481
by report volume (all reactions): 39
reports citing this reaction: 46.2%
death-coded share: Dog
most-affected species

Compiled by PlainBreed

Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Pituitary disorder NOS has 39 reports now versus 39 in that prior snapshot: 0 the same number of (0.0%).

Report change: +0
Death-coded reports: +0
Death-coded share: +0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Pituitary disorder NOS changes

FDA AER · VeDDRA plate

Code 402 VOL-TRACE

VOL-TRACE · DEATH-HOT · LOWER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

VOL-TRACE 39 reports
DEATH-HOT 46.2%
LOWER-Q #1865/2481
PHOTO-FINISH Adaptor, missing
SPECIES-DOG Dog · 33
DRUG-LEAD Trilostane · 36
DESK-WIDE 20 breeds
BOOK-FULL 8/8 fields

Nearest volume peer: Adaptor, missing (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around Pituitary disorder NOS

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

FDA AER report volume · neighbourhood around Pituitary disorder NOS

Pituitary disorder NOS: high death-coded share in the FDA AER plate

Signature read: Pituitary disorder NOS's 46.2% death-coded share is among the highest in the openFDA reaction corpus. Report volume is lower-third scale: 39 named reports in the openFDA extract. Death-coded share is upper-third: 18 of 39 reports (46.2% of named reports). Nearest volume peer: Adaptor, missing (±0 reports). Lead species Dog (33). Lead co-reported drug Trilostane (36).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 33

Horse 4

Cat 2

Breeds Most Affected

Boxer (German Boxer) 6

Retriever - Golden 4

Retriever - Labrador 3

Terrier - Boston 3

Shepherd Dog - Australian 2

Spaniel (unspecified) 2

American Pit Bull Terrier 2

Dachshund (unspecified) 1

Beagle 1

Domestic Longhair 1

Associated Drugs

Trilostane 36

Milbemycin Oxime + Spinosad 4

Imidacloprid + Moxidectin 2

Fluralaner Chew Tablets 2

Grapiprant 2

Omeprazole 2

Probiotic 2

Unspecified Steroid Cream 1

Bismuth Subsalicylate 1

Antibiotic (Unknown) 1

Neem Oil 1

Diazepam 1

Intravenous Lipid Emulsion 1

Phenobarbital 1

Posatex Otic Suspension 1

Moxidectin 1

Insulin Injectable Vial 1

N-Butylscopolaminium Bromide 1

Eastern Encephalomyelitis Virus, Killed Virus + Tetanus Toxoid + West Nile Virus, Killed Virus + Western Encephalomyelitis Virus, Killed Virus 1

Protamine Zinc Recombinant Human Insulin 1

What to do with this reaction

Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
Browse the full reaction directory to compare report counts across reaction types. All reactions

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Pituitary disorder NOS (#1865 of 2,481 by report volume); death-coded 46.2%. PlainBreed reaction plate · death-coded share stamp 46.2% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →