Reaction profile

The FDA adverse-event record for low platelet count

2,082 FDA adverse-event reports reference low platelet count (VeDDRA 161). See the species, breeds, and drugs most associated with it below.

2,082
reports citing this reaction
27.1%
death-coded share
Dog
most-affected species
Oclacitinib Maleate
most-associated drug
Verify with FDA CVM →
2,082
Total Reports
564
Deaths
27.1%
Death Rate

Species Most Affected

Dog 1,746
Cat 324
Horse 11
Ferret 1

Breeds Most Affected

Domestic Shorthair 214
Retriever - Labrador 214
Crossbred Canine/dog 120
Retriever - Golden 113
Shepherd Dog - German 99
Shepherd Dog - Australian 55
Chihuahua 48
Terrier - Yorkshire 42
Shih Tzu 39
Boxer (German Boxer) 37

Associated Drugs

Oclacitinib Maleate 202
Maropitant Citrate 189
Carprofen 182
Milbemycin Oxime + Spinosad 174
Bedinvetmab 141
Prednisone 135
Moxidectin 132
Afoxolaner 128
Gabapentin 107
Doxycycline 103
Cefovecin 96
Ivermectin + Pyrantel As Pamoate Salt 87
Fluralaner Chew Tablets 77
Enrofloxacin 72
Meloxicam 70
Metronidazole 61
Milbemycin Oxime + Praziquantel 60
Polysulfated Glycosaminoglycan 58
Lotilaner 57
Grapiprant 56

Low platelet count Reaction Insights

2,082 reports name Low platelet count; 564 recorded a death outcome (27.1% of reported events, not a population-level mortality rate). VeDDRA code: 161.

By species: Dog (1,746 reports), Cat (324 reports), Horse (11 reports). By breed: Domestic Shorthair (214), Retriever - Labrador (214), Crossbred Canine/dog (120).

Most co-reported drugs: Oclacitinib Maleate (202 reports), Maropitant Citrate (189 reports), Carprofen (182 reports), Milbemycin Oxime + Spinosad (174 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.