Reaction profile

The FDA adverse-event record for low platelet count

2,247 FDA reports name low platelet count, a high-volume reaction in the CVM extract (VeDDRA 161). Plate stamps and neighbourhood peers follow.

#207 of 2,481
by report volume (all reactions)
2,247
reports citing this reaction
26.9%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Low platelet count has 2,247 reports now versus 2,188 in that prior snapshot: 59 more (2.7%).

Report change
+59
Death-coded reports
+14
Death-coded share
−0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Low platelet count changes

FDA AER · VeDDRA plate

Code 161 VOL-MID

VOL-MID · DEATH-HOT · TOP-DECILE · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 2,247 reports
  • DEATH-HOT 26.9%
  • TOP-DECILE #207/2481
  • PHOTO-FINISH Caps, Abnormal
  • SPECIES-DOG Dog · 1,878
  • DRUG-LEAD Maropitant Citrate · 227
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Caps, Abnormal (±5 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Low platelet count

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Confusion · near2259Stumbling gait · near2252Low platelet count · this re…2247Caps, Abnormal · near2242Renal failure · near2240Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Low platelet count

Low platelet count: high death-coded share in the FDA AER plate

Signature read: 605 death-coded reports is a heavy tail count for Low platelet count in the CVM extract. Report volume is upper-third scale: 2,247 named reports in the openFDA extract. Death-coded share is upper-third: 605 of 2,247 reports (26.9% of named reports). Nearest volume peer: Caps, Abnormal (±5 reports). Lead species Dog (1,878). Lead co-reported drug Maropitant Citrate (227).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 1,878
Cat 356
Horse 12
Ferret 1

Breeds Most Affected

Domestic Shorthair 244
Retriever - Labrador 228
Crossbred Canine/dog 137
Retriever - Golden 127
Shepherd Dog - German 102
Shepherd Dog - Australian 58
Chihuahua 50
Shih Tzu 43
Terrier - Yorkshire 43
Boxer (German Boxer) 41

Associated Drugs

Maropitant Citrate 227
Oclacitinib Maleate 214
Carprofen 196
Milbemycin Oxime + Spinosad 174
Bedinvetmab 163
Prednisone 149
Moxidectin 148
Afoxolaner 141
Gabapentin 123
Doxycycline 111
Cefovecin 99
Ivermectin + Pyrantel As Pamoate Salt 91
Enrofloxacin 81
Fluralaner Chew Tablets 77
Meloxicam 75
Metronidazole 68
Polysulfated Glycosaminoglycan 64
Milbemycin Oxime + Praziquantel 63
Grapiprant 63
Anti-Il31 Mab Mcs Lot #1283563 61

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Low platelet count, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (2,247 here).

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Low platelet count (#207 of 2,481 by report volume); death-coded 26.9%. PlainBreed reaction plate · death-coded report count stamp 605 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →