Erosion

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VeDDRA Code: 945

80 adverse event reports referencing this reaction

80
Total Reports
3
Deaths
380.0%
Death Rate

Species Most Affected

Dog 54
Cat 25
Horse 1

Breeds Most Affected

Domestic Shorthair 12
Retriever - Labrador 4
Shepherd Dog - German 4
Domestic Mediumhair 3
Terrier (unspecified) 3
Ragdoll 3
Crossbred Canine/dog 3
Terrier - Yorkshire 3
Terrier - Jack Russell 2
Retriever - Golden 2

Associated Drugs

Prednisone 12
Oclacitinib Maleate 11
Unspecified 10
Cefovecin 9
Selamectin 7
Frunevetmab 7
Maropitant Citrate 6
Famotidine 5
Cefpodoxime Proxetil 5
Carprofen 5
Gabapentin 5
Meloxicam 4
Diphenhydramine Hcl 4
Diphenhydramine 4
Dexmedetomidine 4
Milbemycin Oxime + Spinosad 3
Spinosad 3
Rabies Vaccine 3
Ketoconazole 3
Afoxolaner 3

Data Summary

Metric Value
Total reports referencing reaction 80
Reports with fatal outcome 3
Case-fatality rate (reported events) 380.0%
Species observed 3
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 945.

Erosion Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 80 adverse event reports that reference Erosion as a reaction term, including 3 reports with a death outcome — a 380.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 945, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Erosion appears most frequently in reports for Dog (54 reports), Cat (25 reports), Horse (1 reports) — with Dog dominating at 54 entries. Within those species, the breeds most often named alongside this reaction are Domestic Shorthair (12), Retriever - Labrador (4), Shepherd Dog - German (4). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Erosion are Prednisone (12 reports), Oclacitinib Maleate (11 reports), Unspecified (10 reports), Cefovecin (9 reports), with Prednisone appearing alongside this reaction in 12 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial