Reaction profile

The FDA adverse-event record for central vestibular disorder

69 FDA adverse-event reports reference central vestibular disorder (VeDDRA 2471). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1581 of 2,481
by report volume (all reactions)
69
reports citing this reaction
20.3%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Central vestibular disorder has 69 reports now versus 67 in that prior snapshot: 2 more (3.0%).

Report change
+2
Death-coded reports
+1
Death-coded share
+0.9 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Central vestibular disorder changes

FDA AER · VeDDRA plate

Code 2471 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 69 reports
  • DEATH-HOT 20.3%
  • MID-PACK #1581/2481
  • PHOTO-FINISH Biliary sludge
  • SPECIES-DOG Dog · 65
  • DRUG-LEAD Bedinvetmab · 19
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Biliary sludge (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Central vestibular disorder

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Application site warm… · near70Biliary sludge · near69Central vestibular di… · thi…69Eardrum rupture · near69Paraesthesia · near69Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Central vestibular disorder

What the FDA AER plate says about Central vestibular disorder

Signature read: report volume at 69 (#1581 of 2,481) is the standout scale stamp on Central vestibular disorder. Report volume sits in the middle third of the reaction corpus. 14 of 69 reports were death-coded (20.3% of named reports, not a population mortality rate). Nearest volume peer: Biliary sludge (±0 reports). Lead species Dog (65). Lead co-reported drug Bedinvetmab (19).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Bedinvetmab appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 65
Cat 4

Breeds Most Affected

Crossbred Canine/dog 7
Dog (unknown) 7
Retriever - Golden 5
Shepherd Dog - Australian 4
Domestic Shorthair 3
Shepherd Dog - German 3
Shih Tzu 3
Schnauzer - Miniature 3
Retriever - Labrador 3
Weimaraner 2

Associated Drugs

Bedinvetmab 19
Maropitant Citrate 8
Fluralaner Chew Tablets 6
Oclacitinib Maleate 5
Selamectin 4
Afoxolaner 4
Trilostane 4
Carprofen 4
Meclizine 4
Cyclosporine 3
Verdinexor 3
Gabapentin 3
Fluralaner 13.64% 12-Week Chew 3
Moxidectin 3
Grapiprant 3
Betamethasone + Gentamicin 3
Afoxolaner 68 Mg Chewable Tablets 2
Metronidazole 2
Ivermectin + Pyrantel As Pamoate Salt 2
Milbemycin Oxime + Praziquantel 2

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Central vestibular disorder, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (69 here).

Similar death-coded share

Nearest other reactions by death-coded share (20.3% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Central vestibular disorder (#1581 of 2,481 by report volume); death-coded 20.3%. PlainBreed reaction plate · report volume stamp 69 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →