Reaction profile

The FDA adverse-event record for central vestibular disorder

63 FDA adverse-event reports reference central vestibular disorder (VeDDRA 2471). See the species, breeds, and drugs most associated with it below.

63
reports citing this reaction
20.6%
death-coded share
Dog
most-affected species
Bedinvetmab
most-associated drug
Verify with FDA CVM →
63
Total Reports
13
Deaths
20.6%
Death Rate

Species Most Affected

Dog 59
Cat 4

Breeds Most Affected

Crossbred Canine/dog 7
Dog (unknown) 5
Retriever - Golden 5
Shepherd Dog - Australian 4
Domestic Shorthair 3
Shepherd Dog - German 3
Shih Tzu 3
Retriever - Labrador 3
Weimaraner 2
Spaniel - Springer English 2

Associated Drugs

Bedinvetmab 17
Fluralaner Chew Tablets 6
Selamectin 4
Afoxolaner 4
Trilostane 4
Maropitant Citrate 4
Carprofen 4
Cyclosporine 3
Oclacitinib Maleate 3
Verdinexor 3
Gabapentin 3
Fluralaner 13.64% 12-Week Chew 3
Grapiprant 3
Afoxolaner 68 Mg Chewable Tablets 2
Metronidazole 2
Ivermectin + Pyrantel As Pamoate Salt 2
Milbemycin Oxime + Praziquantel 2
Prednisone 2
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 2
Welactin 2

Central vestibular disorder Reaction Insights

63 reports name Central vestibular disorder; 13 recorded a death outcome (20.6% of reported events, not a population-level mortality rate). VeDDRA code: 2471.

By species: Dog (59 reports), Cat (4 reports). By breed: Crossbred Canine/dog (7), Dog (unknown) (5), Retriever - Golden (5).

Most co-reported drugs: Bedinvetmab (17 reports), Fluralaner Chew Tablets (6 reports), Selamectin (4 reports), Afoxolaner (4 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.