Reaction profile

The FDA adverse-event record for skin and tissue infection nos

718 FDA adverse-event reports reference skin and tissue infection nos (VeDDRA 1755). See the species, breeds, and drugs most associated with it below.

718
reports citing this reaction
8.6%
death-coded share
Dog
most-affected species
Oclacitinib Maleate
most-associated drug
Verify with FDA CVM →
718
Total Reports
62
Deaths
8.6%
Death Rate

Species Most Affected

Dog 629
Cat 63
Cattle 8
Horse 6
Goat 4
Human 4
Chicken 2
Unknown 1
Donkey 1

Breeds Most Affected

Retriever - Labrador 78
Dog (unknown) 42
Domestic Shorthair 38
Shepherd Dog - German 31
Crossbred Canine/dog 27
Shih Tzu 27
Retriever - Golden 22
Boxer (German Boxer) 20
Shepherd Dog - Australian 18
Bulldog 18

Associated Drugs

Oclacitinib Maleate 196
Milbemycin Oxime + Spinosad 103
Bedinvetmab 66
Trilostane 51
Carprofen 49
Anti-Il31 Mab Mcs Lot #1283563 40
Milbemycin Oxime + Praziquantel 38
Gabapentin 32
Prednisone 30
Afoxolaner 30
Cyclosporine 28
Cephalexin 26
Cefpodoxime Proxetil 25
Pyrantel Pamoate;Sarolaner 25
Spinosad 21
Cefovecin 20
Selamectin 20
Maropitant Citrate 20
Cefpodoxime 19
Fluralaner 13.64% 12-Week Chew 19

Skin and tissue infection NOS Reaction Insights

718 reports name Skin and tissue infection NOS; 62 recorded a death outcome (8.6% of reported events, not a population-level mortality rate). VeDDRA code: 1755.

By species: Dog (629 reports), Cat (63 reports), Cattle (8 reports). By breed: Retriever - Labrador (78), Dog (unknown) (42), Domestic Shorthair (38).

Most co-reported drugs: Oclacitinib Maleate (196 reports), Milbemycin Oxime + Spinosad (103 reports), Bedinvetmab (66 reports), Trilostane (51 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.