Reaction profile

The FDA adverse-event record for skin and tissue infection nos

777 FDA reports name skin and tissue infection nos, a high-volume reaction in the CVM extract (VeDDRA 1755). Plate stamps and neighbourhood peers follow.

#468 of 2,481
by report volume (all reactions)
777
reports citing this reaction
8.8%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Skin and tissue infection NOS has 777 reports now versus 755 in that prior snapshot: 22 more (2.9%).

Report change
+22
Death-coded reports
+3
Death-coded share
+0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Skin and tissue infection NOS changes

FDA AER · VeDDRA plate

Code 1755 VOL-MID

VOL-MID · DEATH-PAR · UPPER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 777 reports
  • DEATH-PAR 8.8%
  • UPPER-Q #468/2481
  • PHOTO-FINISH Diabetes
  • SPECIES-DOG Dog · 678
  • DRUG-LEAD Oclacitinib Malea… · 212
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Diabetes (±0 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Skin and tissue infection NOS

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Injection site bleedi… · near780Diabetes · near777Skin and tissue infec… · thi…777Hair shedding · near774Hepatopathy · near774Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Skin and tissue infection NOS

What the FDA AER plate says about Skin and tissue infection NOS

Signature read: 777 reports place Skin and tissue infection NOS in the upper third of FDA AER volume (#468 of 2,481). Report volume is upper-third scale: 777 named reports in the openFDA extract. 68 of 777 reports were death-coded (8.8% of named reports, not a population mortality rate). Nearest volume peer: Diabetes (±0 reports). Lead species Dog (678). Lead co-reported drug Oclacitinib Maleate (212).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Oclacitinib Maleate appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 678
Cat 70
Horse 8
Cattle 8
Goat 4
Human 4
Chicken 2
Unknown 1
Donkey 1
Pig 1

Breeds Most Affected

Retriever - Labrador 84
Dog (unknown) 47
Domestic Shorthair 43
Shepherd Dog - German 37
Shih Tzu 30
Crossbred Canine/dog 28
Retriever - Golden 26
Boxer (German Boxer) 22
Shepherd Dog - Australian 19
Terrier - Bull - American Pit 19

Associated Drugs

Oclacitinib Maleate 212
Milbemycin Oxime + Spinosad 103
Bedinvetmab 78
Trilostane 55
Carprofen 55
Anti-Il31 Mab Mcs Lot #1283563 43
Milbemycin Oxime + Praziquantel 43
Gabapentin 38
Prednisone 36
Cyclosporine 33
Afoxolaner 32
Pyrantel Pamoate;Sarolaner 29
Cephalexin 27
Cefpodoxime Proxetil 26
Ilunocitinib 24
Cefpodoxime 23
Maropitant Citrate 23
Spinosad 21
Selamectin 21
Fluralaner 13.64% 12-Week Chew 21

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Skin and tissue infection NOS, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (777 here).

Similar death-coded share

Nearest other reactions by death-coded share (8.8% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Skin and tissue infection NOS (#468 of 2,481 by report volume); death-coded 8.8%. PlainBreed reaction plate · report volume stamp 777 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →